The RESPIRE trials: Two phase III, randomized, multicentre, placebo-controlled trials of Ciprofloxacin Dry Powder for Inhalation (Ciprofloxacin DPI) in non-cystic fibrosis bronchiectasis

Aksamit Timothy; Bandel Tiemo-Joerg; Criollo Margarita; De Soyza Anthony; Elborn J. Stuart; Operschall Elisabeth; Polverino Eva; Roth Katrin; Winthrop Kevin L.; Wilson Robert

首页> 外文期刊>Contemporary clinical trials >The RESPIRE trials: Two phase III, randomized, multicentre, placebo-controlled trials of Ciprofloxacin Dry Powder for Inhalation (Ciprofloxacin DPI) in non-cystic fibrosis bronchiectasis

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The RESPIRE trials: Two phase III, randomized, multicentre, placebo-controlled trials of Ciprofloxacin Dry Powder for Inhalation (Ciprofloxacin DPI) in non-cystic fibrosis bronchiectasis

机译：呼吸试验：三相III，随机化，多期式，加元对照对照试验，用于吸入（环丙沙星DPI）在非囊性纤维化支气管扩张中的吸入（环丙沙星DPI）

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The primary goals of long-term disease management in non-cystic fibrosis bronchiectasis (NCFB) are to reduce the number of exacerbations, and improve quality of life. However, currently no therapies are licensed for this. Ciprofloxacin Dry Powder for Inhalation (Ciprofioxacin DPI) has potential to be the first long-term intermittent therapy approved to reduce exacerbations in NCFB patients.

机译：长期疾病管理中的非囊性纤维化支气管扩张（NCFB）的主要目标是减少加剧的数量，提高生活质量。但是，目前没有许可疗法。用于吸入的环丙沙星干粉（CiProfioxacin DPI）具有批准的第一个长期间歇性治疗，以减少NCFB患者的恶化。

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来源
《Contemporary clinical trials》 |2017年第2017期|共8页
作者
Aksamit Timothy; Bandel Tiemo-Joerg; Criollo Margarita; De Soyza Anthony; Elborn J. Stuart; Operschall Elisabeth; Polverino Eva; Roth Katrin; Winthrop Kevin L.; Wilson Robert;
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作者单位

Mayo Clin Pulm Dis &

Crit Care Med Rochester MN USA;

Bayer Pharma AG Wuppertal Germany;

Bayer Inc Mississauga ON Canada;

Newcastle Univ Newcastle Upon Tyne Tyne &

Wear England;

Royal Brompton Hosp Host Def Unit London England;

Bayer Pharma AG Berlin Germany;

Hosp Univ Vall dHebron HUVH Inst Recerca Vall dHebron VHIR Barcelona Spain;

Bayer Pharma AG Berlin Germany;

Oregon Hlth &

Sci Univ Portland OR 97201 USA;

Royal Brompton Hosp Host Def Unit London England;

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原文格式 PDF
正文语种 eng
中图分类诊断学;
关键词
Bronchiectasis; Ciprofioxacin Dry Powder for Inhalation; Aerosolized antibiotics; Respiratory infections; Randomized controlled trial; Exacerbations;

机译：支气管扩张;CiProfioxacin干粉吸入;雾化抗生素;呼吸道感染;随机对照试验;加剧;

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1. The RESPIRE trials: Two phase III, randomized, multicentre, placebo-controlled trials of Ciprofloxacin Dry Powder for Inhalation (Ciprofloxacin DPI) in non-cystic fibrosis bronchiectasis [J] . Aksamit Timothy, Bandel Tiemo-Joerg, Criollo Margarita, Contemporary clinical trials . 2017,第期

机译：呼吸试验：三相III，随机化，多期式，加元对照对照试验，用于吸入（环丙沙星DPI）在非囊性纤维化支气管扩张中的吸入（环丙沙星DPI）
2. RESPIRE 1: a phase III placebo-controlled randomised trial of ciprofloxacin dry powder for inhalation in non-cystic fibrosis bronchiectasis [J] . De Soyza Anthony, Aksamit Timothy, Bandel Tiemo-Joerg, The European respiratory journal : . 2018,第1期

机译：呼吸1：III期安慰剂控制的环丙沙星干粉中的无囊性纤维化支气管切除粉末
3. RESPIRE 2: a phase III placebo-controlled randomised trial of ciprofloxacin dry powder for inhalation in non-cystic fibrosis bronchiectasis [J] . Aksamit Timothy, De Soyza Anthony, Bandel Tiemo-Joerg, The European respiratory journal : . 2018,第1期

机译：呼吸2：III期安慰剂控制的环丙沙星干粉随机试验，用于吸入非囊性纤维化支气管切除术
4. A Phase II, Randomized, Double-Blind, Placebo-Controlled Trial of Fish Oil (Eicosapentaenoic Acid and Docosahexaenoic Acid) on Lung and Systemic Inflammation in Patients with Acute Lung Injury. [D] . Stapleton, Renee Doney. 2010

机译：鱼油（二十碳五烯酸和二十二碳六烯酸）对急性肺损伤患者的肺和全身炎症的II期，随机，双盲，安慰剂对照试验。
5. Ciprofloxacin dry powder for inhalation in non-cystic fibrosis bronchiectasis: a phase II randomised study [O] . Robert Wilson, Tobias Welte, Eva Polverino, -1

机译：环丙沙星干粉用于非囊性纤维化支气管扩张的吸入：II期随机研究
6. RESPIRE 2: a phase III placebo-controlled randomised trial of ciprofloxacin dry powder for inhalation in non-cystic fibrosis bronchiectasis [O] . Timothy Aksamit, Anthony De Soyza, Tiemo-Joerg Bandel, 2018

机译：呼吸2：III期安慰剂控制的环丙沙星干粉随机试验，用于在非囊性纤维化支气管扩张中吸入

The RESPIRE trials: Two phase III, randomized, multicentre, placebo-controlled trials of Ciprofloxacin Dry Powder for Inhalation (Ciprofloxacin DPI) in non-cystic fibrosis bronchiectasis

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