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首页> 外文期刊>Cornea >Design and Outcomes of a Novel Keratoprosthesis: Addressing Unmet Needs in End-Stage Cicatricial Corneal Blindness
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Design and Outcomes of a Novel Keratoprosthesis: Addressing Unmet Needs in End-Stage Cicatricial Corneal Blindness

机译：一种新型角化划分性的设计和结果：在最终阶段的光谱角膜盲症中解决未满足的需求

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Purpose: The most commonly applied prosthetic devices for corneal blindness in the setting of severe cicatricial keratoconjunctivitis are the Boston keratoprosthesis type II and the modified osteo-odonto-keratoprosthesis, with these requiring either normal eyelid skin or a healthy cuspid tooth, respectively. For patients with neither attribute, we developed a new keratoprosthesis device combining positive aspects of both Boston keratoprosthesis type II and modified osteo-odonto-keratoprosthesis, which we have named the "Lux." Methods: Short-term postoperative outcomes for the Lux keratoprosthesis, best-corrected visual acuity (BCVA), device retention, and complications, were examined in a retrospective case series of 9 eyes of 9 patients implanted at 4 centers. Results: Seven of 9 (77.8%) eyes had cicatricial corneal blindness due to autoimmune disease and 2 (22.2%) from severe burns. Preoperative BCVA was = 1 therapeutic keratoplasty. One patient had 19 previous eye surgeries. The mean duration of postoperative follow-up was 18.7 months (range 7-28 months). BCVA of >= 20/200 was achieved in all 9 patients, with 2 (22.2%) reaching 20/20 at the last examination, and all 9 (100%) of the devices were retained. One recipient developed a retinal detachment 2 months after implantation. Two (22.2%) patients required placement of a glaucoma drainage device. Conclusions: The Lux keratoprosthesis was developed for patients with severe cicatricial keratoconjunctivitis who were otherwise not candidates for existing keratoprosthesis designs. Short-term outcomes after implantation of the Lux keratoprosthesis were encouraging.
机译：目的：在严重的光谱角膜炎炎环境中的角膜盲剂中最常用的假肢装置是波士顿角涂层型II型和改性的骨科 - odonto-KeratoSprosis，这些试剂分别需要正常的眼睑皮肤或健康的囊齿。对于既没有属性的患者，我们开发了一种新的角化划分性装置，组合了波士顿角划伤型II型的阳性方面，并改性骨科 - odonto-KeratoStrosthesis，我们已经命名为“勒克斯”。方法：在植入4个中心的9名患者的9名患者的回顾性案例系列中，在9名患者的9只眼睛中检查了XeratOpsthesis的短期术后结果，最佳纠正的视力（BCVA），装置保留和并发症。结果：9例（77.8％）眼睛有7个（77.8％）由于自身免疫性疾病，2（22.2％）来自严重烧伤。术前BCVA是= 1个治疗性角膜术。一名患者有19个以前的眼科手术。术后随访的平均持续时间为18.7个月（范围7-28个月）。在所有9名患者中达到了> = 20/200的BCVA，最后一次检查达到20/20的2（22.2％），保留了所有9（100％）的装置。一个接收者在植入后2个月开发了视网膜脱离。两种（22.2％）患者需要放置青光眼引流装置。结论：为患有严重瘢痕疙瘩患者的患者开发了Lux Keratemosthesis，否则没有候选KeratoStrosthesis设计的候选者。植入勒克斯划分基质后的短期结果令人鼓舞。

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