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首页> 外文期刊>Current Opinion in Neurobiology >Mixed selectivity encoding and action selection in the prefrontal cortex during threat assessment
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Mixed selectivity encoding and action selection in the prefrontal cortex during threat assessment

机译:在威胁评估期间预前期皮质中的混合选择性编码和动作选择

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摘要

The medial prefrontal cortex (mPFC) regulates expression of emotional behavior. The mPFC combines multivariate information from its inputs, and depending on the imminence of threat, activates downstream networks that either increase or decrease the expression of anxiety-related motor behavior and autonomic activation. Here, we selectively highlight how subcortical input to the mPFC from two example structures, the amygdala and ventral hippocampus, help shape mixed selectivity encoding and action selection during emotional processing. We outline a model where prefrontal subregions modulate behavior along orthogonal motor dimensions, and exhibit connectivity that selects for expression of one behavioral strategy while inhibiting the other.
机译:内侧前额叶皮质(MPFC)调节情绪行为的表达。 MPFC将多变量信息与其输入组合,并根据威胁的常见,激活下游网络,以增加或减少焦虑相关电机行为和自主激活的表达。 在这里,我们选择性地突出显示来自两个示例结构,Amygdala和ventrals海马的MPFC的子质度点,帮助在情绪处理期间提高混合选择性编码和动作选择。 我们概述了一个模型,其中前额落子区域沿正交电机尺寸调制行为,并且表现出选择用于表达一种行为策略的连接,同时抑制另一个行为策略。

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