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首页> 外文期刊>Current Opinion in Neurobiology >Mutual inhibition of lateral inhibition: a network motif for an elementary computation in the brain
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Mutual inhibition of lateral inhibition: a network motif for an elementary computation in the brain

机译:横向抑制的互抑制:脑中基本计算的网络图案

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摘要

A series of classical studies in non-human primates has revealed the neuronal activity patterns underlying decision making. However, the circuit mechanisms for such patterns remain largely unknown. Recent detailed circuit analyses in simpler neural systems have started to reveal the connectivity patterns underlying analogous processes. Here we review a few of these systems that share a particular connectivity pattern, namely mutual inhibition of lateral inhibition. Close examination of these systems suggests that this recurring connectivity pattern ('network motif') is a building block to enforce particular dynamics, which can be used not only for simple behavioral choice but also for more complex choices and other brain functions. Thus, a network motif provides an elementary computation that is not specific to a particular brain function and serves as an elementary building block in the brain.
机译:非人类主流中的一系列古典研究揭示了神经元活动模式的决策。 然而,这种模式的电路机构仍然很大程度上是未知的。 最近在更简单的神经系统中的详细电路分析已经开始揭示潜在的类似过程的连接模式。 在这里,我们审查了一些共享特定连通模式的这些系统,即横向抑制的相互抑制。 对这些系统的密切检查表明,这种重复的连接模式('网络图案')是强制执行特定动态的构建块,这不仅可以用于简单的行为选择,还可以用于更复杂的选择和其他大脑功能。 因此,网络图案提供了不特异于特定大脑功能的基本计算,并用作大脑中的基本构建块。

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