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首页> 外文期刊>Current oncology reports. >Testicular Choriocarcinoma: a Rare Variant that Requires a Unique Treatment Approach
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Testicular Choriocarcinoma: a Rare Variant that Requires a Unique Treatment Approach

机译：睾丸胆癌：一种需要独特的治疗方法的罕见变种

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Testicular germ cell tumors represent the most common malignancy among young men. While 5-year overall survival and cure for this population is greater than 95 %, choriocarcinoma is an aggressive subtype of this disease with far worse prognosis-5-year survival for choriocarcinoma is less than 80 %. In order to be able to treat these patients appropriately, a provider must recognize characteristic features of choriocarcinoma including elevated human chorionic gonadotropin in a young man with testicular mass; the astute clinician should also know the signs and symptoms of choriocarcinoma syndrome, characterized by bleeding from metastatic sites, which represents a medical emergency and is associated with high morbidity and mortality. Treatment should be directed towards a goal of tumor marker normalization, and patients with refractory disease should be considered for advanced therapies and clinical trials. Choriocarcinoma is a unique and aggressive germ cell malignancy, and these patients require early aggressive treatment to improve their chance of survival.
机译：睾丸生殖细胞肿瘤代表了年轻人中最常见的恶性肿瘤。虽然这一人口的5年整体存活率大于95％，但甘露遗传癌是这种疾病的侵袭性亚型，预后至关重要的预后 - 5年的核心癌的存活率小于80％。为了能够适当地治疗这些患者，提供者必须识别绒毛膜癌的特征特征，包括睾丸质量的年轻人中的人绒毛膜促性腺激素升高;精明的临床医生还应该了解拟核癌综合征的迹象和症状，其特征在于转移性位点，这代表了医疗急诊，与高发病率和死亡率有关。治疗应该针对肿瘤标志物标准化的目标，并且应考虑难治性疾病的患者进行晚期治疗和临床试验。芝麻癌是一种独特而激进的胚芽细胞恶性肿瘤，这些患者需要早期侵略性的治疗，以提高其存活的机会。

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