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Extrapancreatic perineural invasion in pancreatic adenocarcinoma

机译:胰腺癌腺癌的外临加杀伤性侵袭

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Pancreatic ductal adenocarcinoma continues to be a highly lethal disease, despite advances in modern medicine. Curative surgical options continue to carry significant morbidity and offer little improvement in overall 5-year survival. Currently, imaging plays an essential role in the pre-operative evaluation of patients who are undergoing evaluation for resection. However, some pancreatic cancers have particularly aggressive biology, despite appearing resectable by conventional imaging criteria. Imaging biomarkers that serve as surrogates for tumors with such aggressive phenotype have been recently described, namely duodenal invasion and extrapancreatic perineural invasion. In this pictorial review, we will summarize key concepts of extrapancreatic perineural invasion, describe its association with a poor prognosis, and highlight the role of imaging in its detection.
机译:尽管现代医学进展,但胰腺导管腺癌仍然是一种高度致命的疾病。 疗法外科选择继续患上显着的发病率,并在整个5年生存期内提供很少的改善。 目前,成像在接受切除评估评估的患者的术前评估中起重要作用。 然而,尽管通过常规成像标准出现可重视,但一些胰腺癌具有特别侵略性的生物学。 最近已经描述了用作具有这种侵略性表型的肿瘤孕产物的成像生物标志物,即十二指肠侵袭和外临时的麻纹侵袭。 在本文的评论中,我们将总结推荐危险侵袭的关键概念,描述其与预后差的关联,并突出了成像在其检测中的作用。

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