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首页> 外文期刊>Academic radiology >Quantification of aortic regurgitant fraction and volume with multi-detector computed tomography comparison with echocardiography.
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Quantification of aortic regurgitant fraction and volume with multi-detector computed tomography comparison with echocardiography.

机译：具有超声心动图的多探测器计算机断层扫描比较的主动脉反流率和体积的定量。

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RATIONALE AND OBJECTIVES: Evaluate quantification of the aortic regurgitant fraction and volume with computed tomography (CT). MATERIALS AND METHODS: Fifty-three patients with aortic regurgitation (AR) and 29 controls were examined with 64-multi-detector CT coronary angiography and transthoracic echocardiography (TTE). A dedicated software algorithm employing three-dimensional segmentation of left ventricle (LV) and right ventricle (RV) volumes and LV mass was applied. AR volume and fraction was calculated based on RV and LV stroke volumes (SV) and compared with echocardiography. The aortic regurgitant orifice area (ROA) was measured by CT. RESULTS: A good correlation of the AR fraction and AR volume determined by CT compared to echocardiography was found for mild, moderate, and severe AR with 14.2% +/- 9, 28.8% +/- 8, and 57.9% +/- 9 (r = 0.95, P < .001) for AR fraction, and 15.7 mL +/- 11.33 mL +/- 14, and 98.9 mL +/- 36 for AR volume (r = 0.92, P < .0001), respectively. CT correctly classified severity of AR in 93% of patients based of AR-fraction, and in 89% based on AR volume. The sensitivity and specificity of CT were 98% and specificity 90.3%. The specificity improved to 97%, if the ROA by CT was added as diagnostic criterion. CONCLUSION: Aortic regurgitation fraction and volume can be accurately quantified from CT coronary angiography datasets. These parameters can assist clinical management, e.g. in case of pending cardiac surgery decision.
机译：理由和目标：评估主动脉率渐变级分和用计算机断层扫描（CT）的量化。材料和方法：用64-多探测仪CT冠状动脉造影和经脉冲超声心动图（TTE）检查了五十三个主动脉反流（AR）和29例对照。采用左心室（LV）和右心室（RV）体积和LV质量的三维分割的专用软件算法。基于RV和LV中风体积（SV）计算AR体积和分数，并与超声心动图相比。通过CT测量主动脉再静压孔口区域（ROA）。结果：通过CT与超声心动图确定的AR级分和AR体积的良好相关性，用于轻度，中度和严重的AR，14.2％+/- 9,28.8％+/- 8和57.9％+/- 9 （r = 0.95，p <.001）对于AR级分，15.7mL +/- 11.33ml +/- 14和98.9ml +/- 36分别用于AR体积（r = 0.92，p <.0001）。 CT在基于AR级分的93％的患者中正确归类于AR的严重程度，基于AR体积的89％。 CT的敏感性和特异性为98％，特异性90.3％。如果CT的ROA被添加为诊断标准，则特异性提高至97％。结论：主动脉反流率和体积可以从CT冠状动脉血管造影数据集准确定量。这些参数可以帮助临床管理，例如临床管理。在待决心外科决定的情况下。

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