首页> 外文期刊>Academic radiology >Risk Factors for Non-calcified Plaques in Asymptomatic Population
【24h】

Risk Factors for Non-calcified Plaques in Asymptomatic Population

机译:无症状人口中非钙化斑块的危险因素

获取原文
获取原文并翻译 | 示例
           

摘要

Rationale and Objectives: The aims of this study were to assess the prevalence of noncalcified coronary plaques in asymptomatic patients and to investigate the risk factors. Materials and Methods: In this study, 584 patients were recruited prospectively. Patients were classified as having low, intermediate, or high pretest likelihoods of coronary artery disease according to the Morise score. Coronary computed tomographic angiography was performed in all patients using a 320-detector row dynamic-volume computed tomographic scanner. Imaging reconstruction was performed, and the postprocessed data were analyzed. Logistic regression analysis was used to evaluate the relationship between risk factors and the presence of noncalcified plaque. Results: Coronary computed tomographic angiography revealed noncalcified plaques in 38.3% of all patients (224 of 584). The prevalence of noncalcified plaques was significantly higher in patients with calcium scores > 0 (P < .001). Significant differences were found between the degrees of luminal stenosis among patients with low, intermediate, and high pretest likelihoods of coronary artery disease (P = .001), while the prevalence of noncalcified plaques did not differ with the Morise score (P = .08). Noncalcified plaque was associated with hypercholesterolemia (P = .02) and diabetes mellitus (P = .002). Age (P = .47), gender (P = .58), estrogen status (P = .55), smoking (P = .22), hypertension (P = .27), and family history (P = .09) did not differ between patients with and those without noncalcified plaques. Conclusions: Hypercholesterolemia and diabetes mellitus are high risk factors for the prevalence of noncalcified plaques for asymptomatic patients.
机译:理由和目标:本研究的目的是评估无症状患者的非钙化冠状动脉斑块的患病率,并调查风险因素。材料和方法:在本研究中,前瞻性招募了584名患者。根据典范得分,患者被归类为具有低,中间或高冠状动脉疾病的可能性。冠状动脉计算机断层血管造影是在所有患者中进行的,使用320探测器行动态计算的断层扫描仪。进行了成像重建,分析了后处理数据。 Logistic回归分析用于评估风险因素与非钙化斑块之间的关系。结果:冠状动脉计算机断层血管造影揭示了所有患者的38.3%的非钙化斑块(584的224个)。钙分数0(P <0.001)的患者中,非钙化斑块的患病率显着高。在冠状动脉疾病的低,中间患者和高预测可能性的患者患者的腔静脉狭窄程度之间发现了显着差异(p = .001),而非钙化斑块的患病率与德利的得分没有不同(p = .08 )。非钙化斑块与高胆固醇血症(P = .02)和糖尿病(P = .002)有关。年龄(p = .47),性别(p = .58),雌激素状态(p = .55),吸烟(p = .22),高血压(p = .27)和家族史(p = .09)没有非钙化斑块的患者之间没有差异。结论:高胆固醇血症和糖尿病是无症状患者非钙化斑块的患病率的高风险因素。

著录项

  • 来源
    《Academic radiology》 |2012年第5期|共6页
  • 作者单位

    Department of Medical Imaging Jinan Military General Hospital No 25 Shifan Road Jinan 250031;

    Department of Medical Imaging Jinan Military General Hospital No 25 Shifan Road Jinan 250031;

    Department of Medical Imaging Jinan Military General Hospital No 25 Shifan Road Jinan 250031;

    Department of Medical Imaging Jinan Military General Hospital No 25 Shifan Road Jinan 250031;

    Department of Medical Imaging Jinan Military General Hospital No 25 Shifan Road Jinan 250031;

    Department of Medical Imaging Jinan Military General Hospital No 25 Shifan Road Jinan 250031;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 放射医学;
  • 关键词

    Angiography; Computed tomography; Coronary disease; Plaque; Risk factors;

    机译:血管造影;计算断层扫描;冠状病;斑块;危险因素;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号