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首页> 外文期刊>Academic radiology >Noncontrast cardiac computed tomography image-based vertebral bone mineral density. The Multi-Ethnic Study of Atherosclerosis (MESA)
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Noncontrast cardiac computed tomography image-based vertebral bone mineral density. The Multi-Ethnic Study of Atherosclerosis (MESA)

机译：非共同心脏计算断层摄影图像基椎体矿物密度。 动脉粥样硬化（MESA）的多民族研究

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摘要

Rationale and Objectives: Cardiac computer tomography (CT) image-based vertebral bone mineral density (BMD) assessment and the influence of cardiovascular disease risk factors on BMD have not been systematically evaluated, especially in a community-based, multiethnic population. Methods: A cross-sectional study design is used to determine if cardiac CT image is a reliable source to assess vertebral BMD, and a total of 2028 CT images were obtained from the Multi-Ethnic Study of Atherosclerosis, a large, diverse US cohort of adults 45 to 84 years of age. Results: Cardiac CT image allows the rapid assessment of vertebral BMD and related fractures. The mean BMD was significantly higher in men compared with women for thoracic vertebrae (143.2 ?? 41.2 vs 138.7 ?? 42.7 mg/cm3, respectively, P = .014), as well as for lumbar vertebrae (125.0 ?? 37.9 vs 117.2 ?? 39.4 mg/cm3, respectively, P .0001). Thoracic and lumbar BMDs are closely correlated (correlation coefficient 0.87, P .001), independent of age and other confounders including sex and race. African American men had the highest thoracic BMD among all race/ethnicity and sex subgroups. Prevalence of fractures in total vertebrae is 4.2%. Lumbar had approximately 2 times higher prevalence of fracture than thoracic, and the prevalence of vertebral fractures is 1.5% and 3.1% for thoracic and lumbar vertebrae, respectively. Conclusions: Using cardiac CT images to garner and assess vertebral BMD is a feasible and reliable method. Cardiac CT has the additional advantages of evaluate vertebral bone health while assessing cardiovascular disease risk with no extra cost or radiation exposure. ? 2013 AUR.
机译：理由和目标：心脏计算机断层扫描（CT）基础的基于图像的椎体矿物密度（BMD）评估和心血管疾病风险因素对BMD的影响尚未得到系统评估，特别是在基于社区的多民族人群中。方法：使用横截面研究设计来确定心脏CT图像是否是评估椎体BMD的可靠源，并且从动脉粥样硬化的多种族研究中获得了总数的2028ct图像成年人45至84岁。结果：心脏CT图像允许快速评估椎体BMD和相关骨折。与胸椎女性相比，男性的平均bmd显着高（143.2 ?? 41.2 vs 138.7 ?? 42.7mg / cm 3分别，p = .014），以及腰椎（125.0 ?? 37.9 vs 117.2？ ？39.4 mg / cm 3分别，p＆ .0001）。胸部和腰部BMDS密切相关（相关系数0.87，P＆ .001），独立于年龄和其他包括性和种族的混乱。非洲裔美国人在所有种族/种族和性别亚组中都有最高的胸部BMD。总椎骨中骨折的患病率为4.2％。腰部的骨折比胸部患病率较高大约2倍，椎骨骨折的患病率分别为胸椎和腰椎的1.5％和3.1％。结论：使用心脏CT图像来加入并评估椎体BMD是一种可行可靠的方法。心脏CT具有评估椎体健康的额外优点，同时评估无需额外成本或辐射暴露的心血管疾病风险。还2013年AUR。

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  • 来源
    《Academic radiology》 |2013年第5期|共7页
  • 作者

    LiD.; MaoS.S.; KhazaiB.; HyderJ.A.; AllisonM.; McClellandR.; deBoerI.; CarrJ.J.; CriquiM.H.; GaoY.; BudoffM.J.;

  • 作者单位

    Los Angeles Biomedical Research Institute at Harbor-UCLA 1124 W Carson St Torrance CA 90502;

    Los Angeles Biomedical Research Institute at Harbor-UCLA 1124 W Carson St Torrance CA 90502;

    Los Angeles Biomedical Research Institute at Harbor-UCLA 1124 W Carson St Torrance CA 90502;

    Department of Anesthesiology Mayo Clinic Rochester MN United States;

    Department of Family and Preventive Medicine at University of California San Diego School of;

    Department of Biostatistics University of Washington Seattle WA United States;

    Department of Nephrology University of Washington Seattle WA United States;

    Division of Radiologic Sciences Wake Forest University School of Medicine Winston-Salem NC;

    Department of Family and Preventive Medicine at University of California San Diego School of;

    Los Angeles Biomedical Research Institute at Harbor-UCLA 1124 W Carson St Torrance CA 90502;

    Los Angeles Biomedical Research Institute at Harbor-UCLA 1124 W Carson St Torrance CA 90502;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 放射医学;
  • 关键词

    Bone mineral density; Cardiac computed tomography; Vertebral fractures;

    机译：骨密度;心脏计算断层扫描;椎骨骨折;

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