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首页> 外文期刊>Academic radiology >Lobular Carcinoma In Situ of the Breast. Clinical, Radiological, and Pathological Correlation.
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Lobular Carcinoma In Situ of the Breast. Clinical, Radiological, and Pathological Correlation.

机译：乳腺癌原位的乳腺癌。 临床，放射性和病理相关性。

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摘要

Rationale and Objectives: The purpose of this study was to review the imaging findings associated with lobular carcinoma in situ (LCIS) of the breast with clinical and pathological correlation. Materials and Methods: A database search of patients treated at our institution from 2002 to 2011 identified 26 patients with LCIS associated with an imaging abnormality that had imaging available for review. LCIS was diagnosed by core-needle or excision biopsy. Patients subsequently underwent excisional biopsy, mastectomy, or clinical follow-up. Patients' mammography, ultrasonography (US), and magnetic resonance imaging (MRI) images were reviewed using the American College of Radiology Breast Imaging Reporting and Data System lexicon together with relevant clinical and pathology data. Results: The 26 patients had 31 imaging lesions that yielded a histological diagnosis of LCIS by image-guided core-needle biopsy (n = 29) or excision biopsy (n = 2). Twenty-eight of 31 (90%) lesions yielding LCIS had a mammographic abnormality, 3/20 (15%) lesions had a US abnormality, and 6/7 (86%) had an abnormality on contrast-enhanced MRI. Calcifications were the most common mammographic finding, seen in 25/31 (80%) lesions. All three lesions seen on US were masses; the majority was irregular, hypoechoic, avascular, and had posterior shadowing. Non-mass-like enhancement was seen in five (71%) lesions with an MRI abnormality. Two (7%) patients developed subsequent malignancy at follow-up. Conclusion: LCIS can have associated imaging abnormalities, most commonly grouped amorphous calcifications on mammography, a shadowing, avascular, irregular, hypoechoic mass on US, or heterogeneous non-mass-like enhancement with persistent enhancement kinetics on MRI.
机译：理由和目标：本研究的目的是审查与乳房原位（LCIS）与临床和病理相关性的患有小叶癌相关的成像发现。材料和方法：从2002年到2011年在我们的机构治疗的患者的数据库搜索鉴定了26例LCI患者，其与成像异常有用于审查的成像。通过核心针或切除活检诊断LCIS。患者随后接受了促进活检，乳房切除术或临床随访。使用美国放射乳房成像报告和数据系统词汇与相关的临床和病理数据一起审查患者的乳房X线照相术，超声检查（US）和磁共振成像（MRI）图像。结果：26例患者具有31种成像病变，通过图像引导的芯针活检（n = 29）或切除活检（n = 2）产生LCIS的组织学诊断。产生LCIS的28个（90％）病变具有乳房X线监测异常，3/20（15％）病变具有美国异常，6/7（86％）对对比增强MRI具有异常。钙化是最常见的乳房Xmmographic发现，在25/31（80％）病变中。我们身上看到的所有三个病变都是群众;大多数是不规则的，低思想，缺血，并且具有后阴影。在具有MRI异常的五（71％）病变中看到非含重增强。两（7％）患者在随访时期发育了随后的恶性肿瘤。结论：LCIS可以具有相关的成像异常，最常分组的乳房X线照相术分组，阴影，缺血，不规则，低聚物，或者在MRI上具有持续增强动力学的异质非批量生料。

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  • 来源
    《Academic radiology》 |2013年第4期|共8页
  • 作者

    ScogginsM.; KrishnamurthyS.; SantiagoL.; YangW.;

  • 作者单位

    Department of Diagnostic Radiology Unit 1350 The University of Texas MD Anderson Cancer Center;

    Department of Pathology Unit 1350 The University of Texas MD Anderson Cancer Center 1515;

    Department of Diagnostic Radiology Unit 1350 The University of Texas MD Anderson Cancer Center;

    Department of Diagnostic Radiology Unit 1350 The University of Texas MD Anderson Cancer Center;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 放射医学;
  • 关键词

    Biopsy; Lobular Carcinoma in Situ; Mammography; MRI; Sonography;

    机译：活检;原位小叶癌;乳房X线瘤;MRI;超声检查;

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