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首页> 外文期刊>Academic radiology >Diagnostic Performance of a Non-Contrast-Enhanced Magnetic Resonance Imaging Protocol for Potential Living Related Kidney Donors
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Diagnostic Performance of a Non-Contrast-Enhanced Magnetic Resonance Imaging Protocol for Potential Living Related Kidney Donors

机译：潜在生活相关肾脏捐赠者非对比度增强磁共振成像协议的诊断性能

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摘要

Rationale and Objectives: The objective of the study was to evaluate the performance of a non-contrast-enhanced magnetic resonance (MR) imaging protocol for preoperative screening of living related kidney donors. Materials and Methods: Forty consecutive subjects (mean age 52.2 ± 11.3 years, range 29-73 years) underwent MR imaging with T2-weighted sequences (coronal and axial plane), with a non-contrast-enhanced respiratory-gated three-dimensional steady state free precession MR angiography (NCE-MRA) sequence and with contrast-enhanced magnetic resonance MR angiography (CE-MRA) sequences in the arterial and venous phases. Two blinded readers independently assessed arterial and venous anatomy and potential kidney lesions. Results of non-contrast-enhanced images were compared to CE-MRA and in a subgroup of 21 subjects to surgery as standard of reference. Results: Regarding arterial anatomy, NCE-MRA yielded sensitivity, specificity, and accuracy of 100%, 89%, and 91% compared to CE-MRA. Three kidneys were found to have more accessory renal arteries at NCE-MRA than at CE-MRA. In the subgroup of 21 subjects, 1 surgically proven accessory artery was depicted with NCE-MRA but not with CE-MRA. Accuracy of T2-weighted images regarding accessory veins or variant venous course was 99%, with one missed circumaortic vein on T2-weighted images. Two simple cysts were missed on T2-weighted and NCE-MRA but not on CE-MRA images. Conclusion: A non-contrast-enhanced MR imaging protocol including NCE-MRA and T2-weighted images allows for the accurate screening of living related kidney donors and may serve as an alternative to CE-MRA.
机译：理由和目标：该研究的目的是评估非对比增强的磁共振（MR）成像协议的性能，以便术前筛查生活相关的肾脏捐赠者。材料和方法：四十个连续受试者（平均年龄52.2±11.3岁，范围29-73岁）与T2加权序列（冠状和轴向平面）进行MR成像，具有非对比增强的呼吸门控三维稳定状态自由进样MR血管造影（NCE-MRA）序列和具有对比增强的磁共振MR血管造影（CE-MRA）序列在动脉阶段和静脉曲位中。两个盲读者独立评估动脉和静脉解剖和潜在的肾脏病变。将非对比度增强图像的结果与Ce-MRA和21例受试者的亚组进行比较，作为参考标准。结果：关于动脉解剖学，与CE-MRA相比，NCE-MRA产生敏感性，特异性和准确性为100％，89％和91％。发现三个肾脏在NCE-MRA中有比CE-MRA更多的牙科肾动脉。在21个受试者的亚组中，用NCE-MRA描述了1个外科验证的辅助动脉，但没有CE-MRA。关于附件静脉或变体静脉课程的T2加权图像的精度为99％，在T2加权图像上有一个错过的环形静脉。在T2加权和NCE-MRA上错过了两种简单的囊肿，但没有关于CE-MRA图像。结论：具有NCE-MRA和T2加权图像的非对比增强MR成像协议允许准确筛查生活相关的肾脏供体，并可作为CE-MRA的替代品。

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  • 来源
    《Academic radiology》 |2013年第4期|共8页
  • 作者

    GoettiR.; BaumuellerS.; AlkadhiH.; ClavienP.-A.; SchiesserM.; PfammatterT.; HunzikerR.; PuippeG.;

  • 作者单位

    Institute of Diagnostic and Interventional Radiology University Hospital Zurich Raemistrasse 100;

    Institute of Diagnostic and Interventional Radiology University Hospital Zurich Raemistrasse 100;

    Institute of Diagnostic and Interventional Radiology University Hospital Zurich Raemistrasse 100;

    Division of Visceral and Transplant Surgery University Hospital Zurich Raemistrasse 100 8091;

    Division of Visceral and Transplant Surgery University Hospital Zurich Raemistrasse 100 8091;

    Institute of Diagnostic and Interventional Radiology University Hospital Zurich Raemistrasse 100;

    Institute of Diagnostic and Interventional Radiology University Hospital Zurich Raemistrasse 100;

    Institute of Diagnostic and Interventional Radiology University Hospital Zurich Raemistrasse 100;

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  • 正文语种 eng
  • 中图分类 放射医学;
  • 关键词

    Angiography; Contrast media; Magnetic resonance imaging; Organ donors;

    机译：血管造影;对比度介质;磁共振成像;器官捐赠者;

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