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BMI-Based Radiation Dose Reduction in CT Colonography

机译：基于BMI的辐射剂量降低CT结肠

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摘要

Rationale and Objectives: There is potential for x-ray dose reduction in computed tomography colonography (CTC) relative to body mass index (BMI). We evaluated the association between BMI and three-dimensional (3D) CTC image quality to assess the potential utility of BMI as the basis for radiation dose reduction in CTC. Materials and Methods: Ninety-six consecutive patients underwent CTC and were randomized for scanning at 15 or 30 mAs. Extremely obese patients (BMI > 50) were excluded. Each patient was scanned supine and prone on a multidetector CT scanner. Postprocessing CTC visualization was performed on a dedicated workstation. Three independent observers assessed 3D image quality using a four-point scale. Image noise was measured in both the abdomen and pelvis. The association between BMI and image noise was examined using random-effects linear regression models. Logistic regression was used to examine the relationship between BMI, mAs, and conspicuity scores. Results: Statistically significant differences in image noise were observed between 15 and 30 mAs in both the abdomen and pelvis, and the difference was greater with increasing BMI. A positive relationship was detected between BMI and noise in the abdomen (P <.001) and pelvis (P <.001). Inverse correlation was identified between BMI and conspicuity scores in the abdomen (P =.01) and pelvis (P <.001). Overall conspicuity scores were reduced for both 15 and 30 mAs groups as BMI increased. Conclusion: The radiation dose for CTC can be reduced by 40% and 70% below commonly employed doses for overweight and normal BMI patients, respectively, by using a BMI-adjusted dose reduction approach. Conspicuity scores dropped in obese patients with reduced dose suggesting that standard accepted doses should be utilized in that group.
机译：基本原理和目标：相对于体重指数（BMI），计算机断层扫描结肠术（CTC）的X射线剂量降低有可能。我们评估了BMI和三维（3D）CTC图像质量之间的关联，以评估BMI的潜在用途作为CTC辐射剂量降低的基础。材料和方法：连续96名患者接受CTC，随机扫描15或30 MAS。不包括极其肥胖的患者（BMI> 50）。每位患者都被扫描仰卧，俯卧在多传输器CT扫描仪上。后处理CTC可视化是对专用工作站进行的。三个独立观察者使用四点比例评估3D图像质量。在腹部和骨盆中测量图像噪声。使用随机效应线性回归模型检查BMI和图像噪声之间的关联。 Logistic回归用于检查BMI，MAS和ConspIduity分数之间的关系。结果：在腹部和骨盆中观察到图像噪音的统计学显着差异，并且随着BMI的增加，差异更大。在BMI和腹部噪声之间检测到阳性关系（P <.001）和骨盆（P <.001）。在腹部的BMI和PinspiCuity评分之间鉴定反态相关性（P = .01）和骨盆（P <.001）。对于BMI增加，15和30个MAS基团的总体上将分数降低了整体的光临评分。结论：通过使用BMI调节剂量还原方法，CTC的辐射剂量可降低40％，低于超重和正常BMI患者的常用剂量。肥胖患者减少剂量减少的患者均表明该组应在该组中使用标准接受剂量。

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  • 来源
    《Academic radiology》 |2013年第4期|共7页
  • 作者

    GinsburgM.; ObaraP.; WiseL.; WroblewskiK.; VannierM.W.; DachmanA.H.;

  • 作者单位

    University of Chicago Medical Center Department of Radiology 5841 S. Maryland Avenue - MC 2026;

    University of Chicago Medical Center Department of Radiology 5841 S. Maryland Avenue - MC 2026;

    University of Chicago Medical Center Department of Radiology 5841 S. Maryland Avenue - MC 2026;

    University of Chicago Medical Center Department of Radiology 5841 S. Maryland Avenue - MC 2026;

    University of Chicago Medical Center Department of Radiology 5841 S. Maryland Avenue - MC 2026;

    University of Chicago Medical Center Department of Radiology 5841 S. Maryland Avenue - MC 2026;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 放射医学;
  • 关键词

    CT colonography; Radiation dose reduction;

    机译：CT结肠术;辐射剂量减少;

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