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Dose-modified 256-MDCT of the abdomen using low tube current and hybrid iterative reconstruction

机译：使用低管电流和混合迭代重建的腹部剂量改性256-MDCT

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摘要

Rationale and Objectives: To evaluate the performance of hybrid iterative reconstruction technique (h-IRT) on image quality (IQ) in abdominal dose-modified (DM) scans in phantom and in patients in comparison to filtered back projection (FBP). Materials and Methods: An anthropomorphic phantom was scanned using various kVp (80-140) and mAs (25-100) settings. Images were reconstructed with FBP and h-IRT levels (1-6). In 69 adults (59.6±13.54years; 20male, 49female), DM computed tomography (CT) scans were performed using 120 kVp and 100-120mAs. In 25/69, 5-mm FBP and h-IRT (levels 1-4 and 5) images were analyzed to validate IQ. The subsequent 44/69 had FBP and h-IRT (level 4) images reconstructed. Two readers evaluated 188 image series for IQ, noise, and artifacts. Objective and subjective data were analyzed using t-test and Wilcoxon signed-rank test, respectively. In 46/69 patients, prior dose CT was available for dose comparison. Results: In the phantom, noise reduction ranged from 12% (h-IRT level 1) to 50% (level 6). In patients, h-IRT level 4 images were rated diagnostic in 69/69 exams but DM-FBP images were found nondiagnostic in 20/69 patients. The size-specific dose estimate (SSDE) was reduced by 55% in the dose-modified CT group, (SSDE:4.55±1.15mGy) over the prior dose protocol (SSDE:10.21±3.5mGy, P<.0001). Conclusion: h-IRT improved IQ in abdominal DM-CT scans in phantom and in patients. Dose improvements were greater in smaller patients than larger ones.
机译：理由和目的：评价对图像质量（IQ）中以虚线腹部剂量改性（DM）扫描杂交迭代重建技术（H-IRT）的性能，并在患者相比，滤波反投影（FBP）。材料和方法：使用不同的kVp（80-140）和MAS（25-100）设置的仿真人体模型进行扫描。图像用FBP和H-IRT水平（1-6）重建。在69名成人（59.6±13.54年; 20male，49female），采用120的kVp和100-120mAs进行DM计算机断层扫描（CT）扫描。在69分之25，5毫米FBP和h-IRT（水平1-4和5）图像进行分析，以验证IQ。随后69分之44有FBP和h-IRT（4级）图像重建。两个读者评价188的图像系列的智商，噪声和失真。客观和主观数据使用t检验和Wilcoxon符号秩检验分析分别，。在六十九分之四十六患者中，现有剂量CT是可用的剂量比较。结果：在所述体模，降噪从12％（H-IRT级别1）范围至50％（第6级）。在患者中，H-IRT级别4的图像被评为在69分之69检查诊断但发现DM-FBP图像六十九分之二十零患者非诊断。大小特异性剂量估计（SSDE）减少了55％的剂量 - 改性CT基，在（SSDE：4.55±1.15mGy）相对于现有的剂量方案（SSDE：10.21±3.5mGy，P <0.0001）。结论：H-IRT在的幽灵，在患者腹部DM-CT扫描，提高智商。剂量改进是更大较小的患者比大的。

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