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Practical Considerations for the Use of Breast MRI for Breast Cancer Evaluation in the Preoperative Setting

机译:在术前设定中使用乳腺癌评估使用乳腺MRI的实际考虑因素

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Preoperative contrast-enhanced (CE) breast magnetic resonance imaging (MRI) remains controversial in the newly diagnosed breast cancer patient. Additional lesions are frequently discovered in these patients with CE breast MRI. As staging and treatment planning evolve to include more information on tumor biology and aggression, so should our consideration of extent of disease. Directing CE breast MRI to those patients most likely to have additional disease may be beneficial. We sought to develop practical guidance for the use of preoperative CE breast MRI in the newly diagnosed breast cancer patient based on recent scientific data. Our review suggests several populations for whom preoperative breast MRI is most likely to find additional disease beyond that seen on conventional imaging. These can be viewed in three categories: (1) tumor biology—patients with invasive lobular carcinoma or aggressive tumors such as triple negative breast cancer (estrogen receptor negative, progesterone receptor negative, and human epidermal growth factor receptor 2 (HER2) negative) and HER2 positive tumors; (2) patient characteristics—dense breast tissue or younger age, especially those age ]]>
机译:术前对比度增强(CE)乳房磁共振成像(MRI)在新诊断患者患乳腺癌患者中仍存在争议。这些CE乳腺MRI患者经常发现额外的病变。作为分期和治疗计划的发展,包括更多关于肿瘤生物学和侵略的信息,因此我们应该考虑疾病程度。将CE乳房MRI引导至那些最有可能具有额外疾病的患者可能是有益的。根据最近的科学数据,我们试图在新诊断的乳腺癌患者中使用术前CE乳房MRI的实际指导。我们的评论表明,几种群体的术前乳房MRI最有可能在传统成像上发现额外的疾病。这些可以用三类观看:(1)肿瘤生物学 - 患有侵袭性小叶癌或激进肿瘤,如三重阴性乳腺癌(雌激素受体阴性,孕酮受体阴性,和人表皮生长因子受体2(HER2)阴性)和HER2阳性肿瘤; (2)患者特征 - 致密乳房组织或较小的年龄,特别是那些年龄]]>

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