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首页> 外文期刊>Acta biomaterialia >Topological design, permeability and mechanical behavior of additively manufactured functionally graded porous metallic biomaterials
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Topological design, permeability and mechanical behavior of additively manufactured functionally graded porous metallic biomaterials

机译：拓扑设计，渗透性和机械性能的含有渐进式多孔金属生物材料

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Recent advances in additive manufacturing (AM) have enabled the fabrication of functionally graded porous biomaterials (FGPBs) for application as orthopedic implants and bone substitutes. Here, we present a step-wise topological design of FGPB based on diamond unit cells to mimic the structure of the femoral diaphysis. The FGPB was manufactured from Ti-6Al-4V powder using the selective laser melting (SLM) technique. The morphological parameters, permeability and mechanical properties of FGPB samples were measured and compared with those of the biomaterials with uniform porous structures based on the same type of the unit cell. The FGPB exhibited a low density (1.9 g/cm(3)), a moderate Young's modulus (10.44 GPa), a high yield stress (170.6 MPa), a high maximum stress (201 MPa) and favorable ductility, being superior to the biomaterials with uniform porous structures in comprehensive mechanical properties. In addition, digital image correlation (DIC) and finite element (FE) simulation were used to unravel the mechanisms governing the deformation and yielding behavior of these biomaterials particularly at the strut junctions. Both DIC and FE simulations confirmed that the deformation and yielding of the FGPB occurred largely in the load-bearing layers but not at the interfaces between layers. Defect-coupled FE models based on solid elements provided further insights into the mechanical responses of the FGPB to compressive loads at both macro- and micro-scales. With the defect-coupled representative volume element model for the FGPB, the Young's modulus and yield stress of the FGPBs were predicted with less than 2% deviations from the experimental data. The study clearly demonstrated the capabilities of combined experimental and computational methods to resolve the uncertainties of the mechanical behavior of FGPBs, which would open up the possibilities of applying various porosity variation strategies for the design of biomimetic AM porous biomaterials.
机译：最近的添加剂制造（AM）的进展使功能渐进的多孔生物材料（FGPBS）的制造能够作为整形外科植入物和骨代替。在这里，我们基于金刚石单元电池介绍FGPB的一步拓扑设计，以模仿股骨骨干的结构。使用选择性激光熔化（SLM）技术从Ti-6Al-4V粉末制成FGPB。测量FGPB样品的形态学参数，渗透性和机械性能，并与基于相同类型的单位细胞的均匀多孔结构的生物材料的形态学参数，与生物材料的形态学进行比较。 FGPB表现出低密度（1.9g / cm（3）），适度的杨氏模量（10.44GPa），高屈服应力（170.6MPa），高最大应力（201 MPa）和良好的延展性，优于具有均匀的多孔结构的生物材料，综合机械性能。此外，使用数字图像相关（DIC）和有限元（FE）模拟来解开针对这些生物材料的变形和产生行为的机制，特别是在支柱连接处。 DIC和FE模拟均证实，FGPB的变形和屈服在很大程度上在承载层中发生，但不在层之间的界面处发生。基于实心元件的缺陷耦合FE模型提供了进一步的见解，进一步了解FGPB的机械响应，以在宏观和微观尺度上的压缩载荷。利用FGPB的缺陷耦合的代表体积元素模型，预测FGPBS的杨氏模量和屈服应力，与实验数据的偏差小于2％。该研究清楚地证明了组合实验和计算方法的能力，以解决FGPBS的机械行为的不确定性，这将开辟应用各种孔隙度变异策略的可能性，以实现仿生米孔的肌瘤生物材料的设计。

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