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3D printing of electrically conductive hydrogels for tissue engineering and biosensors - A review

机译:组织工程与生物传感器的3D印刷导电水凝胶 - 综述

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摘要

Electrically conductive biomaterials are gaining increasing interest owing to their potential to be used in smart, biosensoric and functional tissue-engineered scaffolds and implants. In combination with 3D printing technology, this class of materials might be one of the most advanced approaches towards future medical implants regarding potential functionalities and design possibilities. Conductive hydrogels themselves have been researched for potential sensoric and tissue engineering applications for more than a decade, while the 3D printing of such functional materials is still under early exploration. This review aims to provide a short insight into the most recent developments of 3D printable and electrically conductive hydrogels. It also provides a summary of the last few years of research in this field, with key scope on 3D printing for biomedical applications. The final literature search was conducted in May 2019, with the specific keywords '3D', 'printing', 'conductive', 'hydrogel', 'biocompatible' and combinations of the latter, using advanced search in the databases Scopus (R), Web of Science (R) (Web of Knowledge (R)) and Google Scholar. A total of 491 results were gained, while 19 recent publications were identified with the above mentioned criteria and keywords, which are the studies finally discussed in the paper. The key results have been summarised, and the remaining challenges in the field and the scope for future research activities have been discussed.
机译:由于它们的潜力用于智能,生物传感器和功能组织工程的支架和植入物,导电生物材料正在增加利益。结合3D打印技术,这类材料可能是未来医疗植入物的最先进方法之一,就潜在的功能和设计可能性。对于潜在的感官和组织工程应用,已经研究了导电水凝胶,而超过十年的组织工程应用,而这种功能材料的3D印刷仍在早期勘探下。该审查旨在提供对3D可打印和导电水凝胶的最新发展的简短深入了解。它还提供了该领域过去几年研究的摘要,具有生物医学应用的3D打印关键范围。最终的文献搜索是在2019年5月进行的,具有特定的关键字“3D”,“打印”,“导电”,“流行物”,“生物相容性”和后者的组合,在数据库中使用高级搜索(R)中的高级搜索,科学网(R)(知识网络(R))和Google Scholar。获得了491个结果,而最近的19个出版物是通过上述标准和关键字确定的,这是本文最终讨论的研究。关键结果已被概述,并且已经讨论了该领域的剩余挑战以及未来的研究活动的范围。

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