Intact vitreous humor as a potential extracellular matrix hydrogel for cartilage tissue engineering applications

Lindberg G. C. J.; Longoni A.; Lim K. S.; Rosenberg A. J.; Hooper G. J.; Gawlitta D.; Woodfield T. B. F.

首页> 外文期刊>Acta biomaterialia >Intact vitreous humor as a potential extracellular matrix hydrogel for cartilage tissue engineering applications

【24h】

Intact vitreous humor as a potential extracellular matrix hydrogel for cartilage tissue engineering applications

机译：完整的玻璃体幽默作为软骨组织工程应用的潜在细胞外基质水凝胶

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Decellularisation of tissues, utilising their biochemical cues, poses exciting tissue engineering (TE) opportunities. However, removing DNA from cartilage (dCart) requires harsh treatments due to its dense structure, causing loss of bioactivity and limiting its application as a cartilaginous extra cellular matrix (ECM). In this study, we demonstrate for the first time the successful application of vitreous humor (VH), a highly hydrated tissue closely resembling the glycosaminoglycan (GAG) and collagen composition of cartilage, as an ECM hydrogel to support chondrogenic differentiation.

机译：利用其生化线索的组织的桨细胞造成令人兴奋的组织工程（TE）机会。然而，从软骨（DCART）中除去DNA需要由于其致密结构而苛刻的治疗，导致生物活性丧失并将其应用限制为软骨额外的细胞基质（ECM）。在这项研究中，我们首次证明了玻璃体幽默（VH）的成功应用，一种高度水合组织，与糖胺聚糖（GAG）和软骨胶原蛋白组成紧密相似，作为ECM水凝胶，以支持软骨内分化。

著录项

来源
《Acta biomaterialia》 |2019年第2019期|共14页
作者
Lindberg G. C. J.; Longoni A.; Lim K. S.; Rosenberg A. J.; Hooper G. J.; Gawlitta D.; Woodfield T. B. F.;
展开▼
作者单位

Univ Otago Christchurch Christchurch Regenerat Med &

Tissue Engn CReaTE G Dept Orthopaed Surg &

Univ Med Ctr Utrecht Dept Oral &

Maxillofacial Surg NL-3584 CX Utrecht Netherlands;

Univ Otago Christchurch Christchurch Regenerat Med &

Tissue Engn CReaTE G Dept Orthopaed Surg &

Univ Med Ctr Utrecht Dept Oral &

Maxillofacial Surg NL-3584 CX Utrecht Netherlands;

Univ Otago Christchurch Christchurch Regenerat Med &

Tissue Engn CReaTE G Dept Orthopaed Surg &

Univ Med Ctr Utrecht Dept Oral &

Maxillofacial Surg NL-3584 CX Utrecht Netherlands;

Univ Otago Christchurch Christchurch Regenerat Med &

Tissue Engn CReaTE G Dept Orthopaed Surg &

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类普通生物学;
关键词
Vitreous humor; Biomimetic hydrogels; Cartilage tissue engineering; Extracellular matrix (ECM); Decellularisation; Micro-tissues;

机译：玻璃体幽默;生物摩托的水凝胶;软骨组织工程;细胞外基质（ECM）;脱细胞化;微组织;

相似文献

外文文献
中文文献
专利

1. Intact vitreous humor as a potential extracellular matrix hydrogel for cartilage tissue engineering applications [J] . Lindberg G. C. J., Longoni A., Lim K. S., Acta biomaterialia . 2019,第期

机译：完整的玻璃体幽默作为软骨组织工程应用的潜在细胞外基质水凝胶
2. Extracellular-Matrix-Based and Arg-Gly-Asp-Modified Photopolymerizing Hydrogels for Cartilage Tissue Engineering [J] . Kim Hwan D., Heo Jiseung, Hwang Yongsung, Tissue engineering, Part A . 2015,第3a4期

机译：用于软骨组织工程的基于细胞外基质和Arg-Gly-Asp修饰的光聚合水凝胶
3. Cartilaginous Extracellular Matrix-Modified Chitosan Hydrogels for Cartilage Tissue Engineering [J] . Choi Bogyu, Kim Soyon, Lin Brian, ACS applied materials & interfaces . 2014,第22期

机译：软骨细胞外基质修饰的壳聚糖水凝胶用于软骨组织工程
4. Hybrid Scaffold-reinforced Extracellular Matrix Hydrogels for Cartilage Tissue Engineering [C] . Sonya Sonnenberg, M. Andrew Taylor, Liliana Mellor, Society for Biomaterials annual meeting and exposition . 2015

机译：用于软骨组织工程的杂种支架增强细胞外基质水凝胶。
5. PEG-based hydrogels as chondrocyte carriers for tissue engineered cartilage: Controlling extracellular matrix evolution and integration with native cartilage. [D] . Rice, Mark Andrew. 2006

机译：基于PEG的水凝胶作为组织工程软骨的软骨细胞载体：控制细胞外基质的进化以及与天然软骨的整合。
6. Efficacy of thermoresponsive photocrosslinkable hydrogels derived from decellularized tendon and cartilage extracellular matrix for cartilage tissue engineering [O] . Benjamin B. Rothrauff, Luca Coluccino, Riccardo Gottardi, -1

机译：脱细胞肌腱和软骨细胞外基质衍生的热响应性可光交联的水凝胶对软骨组织工程的功效
7. Chitosan-based hydrogels as extracellular matrix for cartilage tissue engineering: in vitro biological evaluation [O] . Moreira Teixeira, Liliana, Reis, R L, Jin, R., 2008

机译：基于壳聚糖的水凝胶作为软骨组织工程的细胞外基质：体外生物学评估

Intact vitreous humor as a potential extracellular matrix hydrogel for cartilage tissue engineering applications

摘要

著录项

相似文献

相关主题

期刊订阅