Peripheral blood brain-derived neurotrophic factor level and tyrosine kinase B expression on T lymphocytes in systemic lupus erythematosus: Implications for systemic involvement

Tian Bailing; Yang Chunshu; Wang Jianing; Hou Xiaoyu; Zhao Shan; Li Yujia; Yang Pingting

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Peripheral blood brain-derived neurotrophic factor level and tyrosine kinase B expression on T lymphocytes in systemic lupus erythematosus: Implications for systemic involvement

机译：全周血脑血液脑衍生的神经营养因子水平和酪氨酸激酶B表达在Systemic狼疮红斑狼疮中的T淋巴细胞：系统累纳的影响

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Objective: Brain-derived neurotrophic factor (BDNF) has been reported to be involved in the pathogenesis of autoimmune diseases and tyrosine kinase B (TrkB) is the specific receptor for BDNF. Our aim in this study was to investigate serum BDNF level and TrkB expression on peripheral blood T cell surface in patients with systemic lupus erythematosus (SLE) and explore potential relationship between serum BDNF and SLE.

机译：目的：据报道脑衍生的神经营养因子（BDNF）涉及自身免疫疾病的发病机制，酪氨酸激酶B（TRKB）是BDNF的特异性受体。我们在本研究中的目的是探讨血清血液T细胞表面的血清BDNF水平和TRKB表达，患者患有全身性红斑狼疮（SLE），探讨血清BDNF和SLE之间的潜在关系。

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来源
《Cytokine》 |2019年第2019期|共7页
作者
Tian Bailing; Yang Chunshu; Wang Jianing; Hou Xiaoyu; Zhao Shan; Li Yujia; Yang Pingting;
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作者单位

China Med Univ Affiliated Hosp 1 Dept Rheumatol &

Immunol Shenyang 110001 Peoples R China;

China Med Univ Affiliated Hosp 1 Dept Canc Inst 1 Shenyang 110001 Peoples R China;

China Med Univ Affiliated Hosp 1 Dept Rheumatol &

Immunol Shenyang 110001 Peoples R China;

China Med Univ Affiliated Hosp 1 Dept Rheumatol &

Immunol Shenyang 110001 Peoples R China;

China Med Univ Affiliated Hosp 1 Dept Rheumatol &

Immunol Shenyang 110001 Peoples R China;

China Med Univ Affiliated Hosp 1 Dept Rheumatol &

Immunol Shenyang 110001 Peoples R China;

China Med Univ Affiliated Hosp 1 Dept Rheumatol &

Immunol Shenyang 110001 Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类细胞生物学;
关键词
Brain-derived neurotrophic factor tyrosine kinase B; T lymphocyte; Systemic involvement;

机译：脑衍生的神经营养因子酪氨酸激酶B;T淋巴细胞;全身参与;

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1. Peripheral blood brain-derived neurotrophic factor level and tyrosine kinase B expression on T lymphocytes in systemic lupus erythematosus: Implications for systemic involvement [J] . Tian Bailing, Yang Chunshu, Wang Jianing, Cytokine . 2019,第期

机译：全周血脑血液脑衍生的神经营养因子水平和酪氨酸激酶B表达在Systemic狼疮红斑狼疮中的T淋巴细胞：系统累纳的影响
2. Expression and Activation of Proline-Rich Tyrosine Kinase 2 (PYK2) in Peripheral Blood Mononuclear Cells from Patients with Systemic Lupus Erythematosus [J] . M Wang, W Zhang, Y Zhang Journal of International Medical Research . 2009,第5期

机译：来自Systemic Lupus红斑狼疮患者外周血单核细胞中富含富含富含酪氨酸激酶2（PYK2）的表达和活化
3. Serum brain-derived neurotrophic factor levels as a novel biological marker for the activities of psychiatric symptoms in systemic lupus erythematosus. [J] . Ikenouchi Sugita A, Yoshimura R, Okamoto T, The world journal of biological psychiatry: the official journal of the World Federation of Societies of Biological Psychiatry . 2010,第1a2期

机译：血清脑源性神经营养因子水平是系统性红斑狼疮精神症状活动的新型生物学标记。
4. Serum Levels of Leptin in Patients with Systemic Lupus Erythematosus: Correlated with Lupus Activity [C] . XU Ting, JIN Ou-yang, ZHAO Sheng-nan, International Forum on Progress on Post-Genome Technologies(5'IFPT); 20070910-11; Suzhou(CN) . 2007

机译：系统性红斑狼疮患者血清瘦素水平：与狼疮活动相关
5. In vivo Assessment of Bone Microarchitecture and Bone Strength in Systemic Lupus Erythematosus Patients by High-Resolution Peripheral Quantitative Computed Tomography and Finite Element Analysis [D] . Tang, Xiaolin. 2013

机译：高分辨率外周定量CT和有限元分析技术评估系统性红斑狼疮患者的骨微结构和骨强度
6. Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes [O] . Atsuko Ikenouchi-Sugita, Reiji Yoshimura, Nobuhisa Ueda, 2008

机译：系统性红斑狼疮伴器质性脑部改变的神经精神病综合症患者血清脑源性神经营养因子（BDNF）水平持续降低
7. Expression and Activation of Proline-Rich Tyrosine Kinase 2 (PYK2) in Peripheral Blood Mononuclear Cells from Patients with Systemic Lupus Erythematosus [O] . M Wang, W Zhang, Y Zhang 2009

机译：来自Systemic Lupus红斑狼疮患者外周血单核细胞中富含富含富含酪氨酸激酶2（PYK2）的表达和活化

Peripheral blood brain-derived neurotrophic factor level and tyrosine kinase B expression on T lymphocytes in systemic lupus erythematosus: Implications for systemic involvement

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