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首页> 外文期刊>Acta oncologica. >Reproducibility of heart and thoracic wall position in repeated deep inspiration breath holds for radiotherapy of left-sided breast cancer patients
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Reproducibility of heart and thoracic wall position in repeated deep inspiration breath holds for radiotherapy of left-sided breast cancer patients

机译：心脏和胸壁壁垒在重复深深的灵感呼吸中的再现性，用于左侧乳腺癌患者的放射治疗

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Background: Deep inspiration breath hold (DIBH) for radiotherapy of left-sided breast cancer patients can effectively move the heart away from the target and reduce the heart dose compared to treatments in free breathing. This study aims to investigate the positional reproducibility of heart edge (HE) and thoracic wall (TW) during repeated DIBHs.Material and methods: At three occasions, 11 left-sided breast cancer patients were CT imaged during 6 minutes of repeated DIBHs with 60 cine CT series. The series were evenly distributed over three bed positions and for each bed position, the heart edge associated maximum heart distance (MHD) and thoracic wall-associated maximum lung distance (MLD) from a reference line were retrospectively analyzed. The high temporal resolution of the CT series enabled intrinsic heart movements to be resolved from breath hold variations. A body surface laser scanning system continuously extracted the thorax height and displayed it in a pair of goggles for patient feedback. To check for 'fake-breathing' movements, e.g. that the patient lifts its back from the couch to reach DIBH, the couch-to-spine distance was also measured in all CT series.Results: The analysis was done for 1432 cine CTs captured during 292 breath holds. The DIBH moved the heart on average 15 mm in medial direction compared with free breathing. For the three bed positions studied, the mean value of the max range, across all patients, was between 11-13 mm for the MHD and 4-8 mm for the MLD. The MHD variation due to breath hold variation was twice as large as the MHD variation due to intrinsic heart movement. The couch-to-spine distance varied less than 3 mm for all fractions, i.e., no fake-breathing was discovered.Conclusions: The heart edge and thoracic wall reproducibility was high in relation to the medial heart displacement induced by the DIBH.
机译：背景技术：左侧乳腺癌患者放射疗法的深度灵感呼吸持有（Dibh）可以有效地将心脏从目标移开并减少心脏剂量，与自由呼吸的治疗相比。本研究旨在研究心脏边缘（HE）和胸壁（TW）在重复的dibhs期间的位置再现CINE CT系列。该系列均匀地分布在三个床位，每个床位位置，回顾性分析了来自参考线的心边缘相关的最大心距（MHD）和胸壁相关的最大肺距离（MLD）。 CT系列的高时间分辨率使得从呼吸保持变化解决的内部心脏运动。体表激光扫描系统连续提取胸腔高度，并在一对护目镜中显示出患者反馈。检查'假呼吸'运动，例如患者从沙发上抬起它以达到DIBH，在所有CT系列中也测量了沙发脊柱距离。结果：在292次呼吸持有期间捕获的1432 Cine CTS进行分析。与自由呼吸相比，Dibh平均地将心脏平均移动15毫米。对于所研究的三个床位，最大范围的平均值，在所有患者中，MLD的MHD和4-8毫米之间的11-13毫米。由于呼吸变化因子而导致的MHD变化是由于内在心脏运动引起的MHD变化的两倍。所有部分的沙发到脊柱距离变化小于3mm，即，没有发现假呼吸。结论：心边缘和胸壁再现性高于Dibh引起的内侧心脏位移高。

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  • 来源
    《Acta oncologica.》 |2018年第10期|共7页
  • 作者

    Kenneth Wikstrom;

  • 作者单位

    Medical Radiation Physics Department of Biomedical Engineering Medical Physics and IT Uppsala;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 肿瘤学;
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