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首页> 外文期刊>Acta oncologica. >Cone beam CT-based set-up strategies with and without rotational correction for stereotactic body radiation therapy in the liver
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Cone beam CT-based set-up strategies with and without rotational correction for stereotactic body radiation therapy in the liver

机译：基于CT的CT基于肝脏静态体放射治疗的锥形CT的建立策略

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摘要

Background: Accurate patient positioning is crucial in stereotactic body radiation therapy (SBRT) due to a high dose regimen. Cone-beam computed tomography (CBCT) is often used for patient positioning based on radio-opaque markers. We compared six CBCT-based set-up strategies with or without rotational correction. Material and methods: Twenty-nine patients with three implanted markers received 3-6 fraction liver SBRT. The markers were delineated on the mid-ventilation phase of a 4D-planning-CT. One pretreat-ment CBCT was acquired per fraction. Set-up strategy 1 used only translational correction based on manual marker match between the CBCT and planning CT. Set-up strategy 2 used automatic 6 degrees-of-freedom registration of the vertebrae closest to the target. The 3D marker trajectories were also extracted from the projections and the mean position of each marker was calculated and used for set-up strategies 3-6. Translational correction only was used for strategy 3. Translational and rotational corrections were used for strategies 4-6 with the rotation being either vertebrae based (strategy 4), or marker based and constrained to ±3° (strategy 5) or unconstrained (strategy 6). The resulting set-up error was calculated as the 3D root-mean-square set-up error of the three markers. The set-up error of the spinal cord was calculated for all strategies.
机译：背景：由于高剂量方案，准确的患者定位在立体定向体放射治疗（SBRT）中至关重要。锥梁计算机断层扫描（CBCT）通常用于基于无线电不透明标记的患者定位。我们将六种基于CBCT的设置策略与或不具有旋转校正进行了比较。材料和方法：二十九个植入标记的患者接受了3-6分数肝脏SBRT。将标记物在4D规划-CT的中间通气阶段划清。每馏分获得一个预处理的CBCT。设置策略1仅基于CBCT与规划CT之间的手动标记匹配的翻译校正。设置策略2使用最接近目标的椎骨的自动6度自由度。还从突起中提取3D标记轨迹，并且计算每个标记的平均位置并用于设置策略3-6。仅用于策略的翻译校正3.转换和旋转校正用于策略4-6，旋转是基于椎骨（策略4），或基于±3°（策略5）或无约束的标记（策略6）（策略6 ）。生成的设置错误是计算为三个标记的3D根均方设置错误。为所有策略计算脊髓的设置误差。

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