Associations between skin rash, treatment outcome, and single nucleotide polymorphisms in head and neck cancer patients receiving the EGFR-inhibitor zalutumumab: results from the DAHANCA 19 trial

Brondum Line; Alsner Jan; Sorensen Brita Singers; Maare Christian; Johansen Jorgen; Primdahl Hanne; Evensen Jan Folkvard; Kristensen Claus Andrup; Andersen Lisbeth Juhler; Overgaard Jens; Eriksen Jesper Grau

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Associations between skin rash, treatment outcome, and single nucleotide polymorphisms in head and neck cancer patients receiving the EGFR-inhibitor zalutumumab: results from the DAHANCA 19 trial

机译：皮疹，治疗结果和头部癌症患者的皮疹，治疗结果和单核苷酸多态性之间的关联患者接受EGFR抑制剂Zalutumumab：Dahanca 19试验结果

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Purpose: To study the associations between development of moderate to severe skin rash, clinical outcome, and single nucleotide polymorphisms (SNPs) in candidate genes in head and neck cancer patients from the DAHANCA 19 trial receiving the EGFR-inhibitor zalutumumab concurrently with radiation treatment.

机译：目的：研究中度至重度皮疹，临床结果和单核苷酸多态性（SNP）的候选基因的开发与颈部癌患者的候选基因之间的关联与放射治疗同时接受EGFR抑制剂Zalutumumab。

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《Acta oncologica.》 |2018年第9期|共6页
作者
Brondum Line; Alsner Jan; Sorensen Brita Singers; Maare Christian; Johansen Jorgen; Primdahl Hanne; Evensen Jan Folkvard; Kristensen Claus Andrup; Andersen Lisbeth Juhler; Overgaard Jens; Eriksen Jesper Grau;
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Aarhus Univ Hosp Dept Expt Clin Oncol Norrebrogade 44 Bldg 5 DK-8000 Aarhus C Denmark;

Aarhus Univ Hosp Dept Expt Clin Oncol Norrebrogade 44 Bldg 5 DK-8000 Aarhus C Denmark;

Aarhus Univ Hosp Dept Expt Clin Oncol Norrebrogade 44 Bldg 5 DK-8000 Aarhus C Denmark;

Herlev Hosp Dept Oncol Copenhagen Denmark;

Odense Univ Hosp Dept Oncol Odense Denmark;

Aarhus Univ Hosp Dept Oncol Odense Denmark;

Oslo Univ Hosp Radiumhosp Dept Oncol Oslo Norway;

Rigshosp Dept Oncol Copenhagen Denmark;

Aalborg Univ Hosp Dept Oncol Aalborg Denmark;

Aarhus Univ Hosp Dept Expt Clin Oncol Norrebrogade 44 Bldg 5 DK-8000 Aarhus C Denmark;

Aarhus Univ Hosp Dept Expt Clin Oncol Norrebrogade 44 Bldg 5 DK-8000 Aarhus C Denmark;

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1. Associations between skin rash, treatment outcome, and single nucleotide polymorphisms in head and neck cancer patients receiving the EGFR-inhibitor zalutumumab: results from the DAHANCA 19 trial [J] . Brondum Line, Alsner Jan, Sorensen Brita Singers, Acta oncologica. . 2018,第9期

机译：皮疹，治疗结果和头部癌症患者的皮疹，治疗结果和单核苷酸多态性之间的关联患者接受EGFR抑制剂Zalutumumab：Dahanca 19试验结果
2. Single nucleotide polymorphisms in nucleotide excision repair genes, cancer treatment, and head and neck cancer survival. [J] . Annah B Wyss, Mark C Weissler, Christy L Avery, Cancer causes and control: CCC . 2014,第4期

机译：核苷酸切除修复基因，癌症治疗和头颈癌生存中的单核苷酸多态性。
3. DAHANCA 10-Effect of darbepoetin alfa and radiotherapy in the treatment of squamous cell carcinoma of the head and neck. A multicenter, open-label, randomized, phase 3 trial by the Danish head and neck cancer group [J] . Overgaard Jens, Hoff Camilla Molich, Hansen Hanne Sand, Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2018,第1期

机译：Dahanca 10- Darbepoetin Alfa和放疗治疗头颈鳞状细胞癌的疗效。多中心，开放标签，随机，丹麦头和颈部癌群试验
4. Single Nucleotide Polymorphisms: Identification and Association with Breast Cancer Using Biocomputing Approach [C] . Neelofar Sohi, Amardeep Singh International Conference on Intelligent Computing and Control Systems . 2018

机译：单核苷酸多态性：使用生物计算方法与乳腺癌的鉴定和关联。
5. A qualitative descriptive study of patients' experiences of receiving primary radiation treatment for head and neck cancer [D] . McQuestion, Maurene Anne 2006

机译：定性描述性研究头颈癌患者接受一次放射治疗的经验
6. Single nucleotide polymorphisms in nucleotide excision repair genes cancer treatment and head and neck cancer survival [O] . Annah B. Wyss, Mark C. Weissler, Christy L. Avery, -1

机译：核苷酸切除修复基因癌症治疗和头颈癌生存中的单核苷酸多态性
7. Associations between skin rash, treatment outcome, and single nucleotide polymorphisms in head and neck cancer patients receiving the EGFR-inhibitor zalutumumab: results from the DAHANCA 19 trial [O] . Line Brøndum, Jan Alsner, Brita Singers Sørensen, 2018

机译：皮疹，治疗结果和头部癌症患者的皮疹，治疗结果和单核苷酸多态性之间的关联接受EGFR抑制剂Zalutumumab：Dahanca 19审判的结果

Associations between skin rash, treatment outcome, and single nucleotide polymorphisms in head and neck cancer patients receiving the EGFR-inhibitor zalutumumab: results from the DAHANCA 19 trial

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