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首页> 外文期刊>Acta oncologica. >Bridging imaging and therapy: the role of medical physics in development of precision cancer care
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Bridging imaging and therapy: the role of medical physics in development of precision cancer care

机译：桥接成像和治疗：医疗物理学在精密癌症护理开发中的作用

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A number of health disciplines are involved in diagnosing, staging and treating cancer, using a broad array of technologies and treatment approaches. One highly relevant discipline in this field is medical physics, where physics principles and methods are applied to medicine, contributing, in particular, to medical imaging and radiotherapy [1-3]. Magnetic resonance imaging (MRI) and positron emission tomography (PET) can be used to assess disease extension and to localize the most aggressive part of the disease in the patient. Extraction and analysis of imaging profiles of individual patients may further give prognostic information, not necessarily obtained from patient-specific clinical or genetic information [4]. Images from such modalities may further be used as input for planning of surgery and radiotherapy, giving both surgeons and radiation oncologists guidance tools for eradicating the tumor. Furthermore, in radiotherapy, medical images provide the information necessary to delineate the tumor and organs at risk. Radiotherapy is a completely digital process, where developments are seen among others in delivery techniques and image-guided adapted strategies [5-7], With the aim of cancer care to move from the concept of 'one-size-fits-all' to individualized treatment, the term 'Precision cancer care' could also encompass radiotherapy tailored to the individual patient's medical image-based profile in addition to the genetic profile. The progress in imaging and radiotherapy towards precision cancer care relies on the development of dedicated methods for quantitative use of functional images in treatment selection, planning, delivery and response evaluation for the individual patient.
机译：使用广泛的技术和治疗方法，许多卫生学科参与诊断，分期和治疗癌症。该领域的一个高度相关的学科是医学物理学，其中物理原理和方法适用于医学，特别是医学成像和放射治疗[1-3]。磁共振成像（MRI）和正电子发射断层扫描（PET）可用于评估疾病延伸，并在患者中定位疾病的最具侵略性部分。个体患者的成像谱的提取和分析可以进一步提供预后信息，不一定从患者特异性临床或遗传信息中获得[4]。来自这种方式的图像可以进一步用作规划手术和放射治疗的输入，给予外科医生和辐射肿瘤学家用于消除肿瘤的引导工具。此外，在放射疗法中，医学图像提供了描绘肿瘤和器官面临风险所需的信息。放射疗法是一个完全数字化过程，其中在交付技术和图像引导的改编策略中看到了发展的发展，目的是癌症照顾，从“单尺寸适合 - 全部”的概念中移动个性化治疗，除了遗传概况之外，术语“精确癌症护理”术语也可以包括针对个体患者的医学形象的型材量身定制的放射治疗。成像和放疗对精密癌症护理的进展依赖于在治疗选择，规划，递送和响应评估中定量使用功能图像的专用方法的开发。

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