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首页> 外文期刊>Acta ophthalmologica >Morphological changes in the diseased retina on a healthy choroid‐retinal pigment epithelial complex after full macular translocation for exudative age‐related macular degeneration
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Morphological changes in the diseased retina on a healthy choroid‐retinal pigment epithelial complex after full macular translocation for exudative age‐related macular degeneration

机译：渗出性静脉易位后健康脉络膜视网膜色素上皮复合体的患病视网膜的形态学变化

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Abstract Purpose To describe the change in the retinal morphology after full macular translocation ( FMT ) for exudative age‐related macular degeneration ( AMD ) and identify predictive factors for the visual outcome. Methods All patients who underwent FMT from December 2008 through July 2013 were selected. Exclusion criteria were FMT for other disease than AMD , age 60?years, 12?months of follow‐up or no available images. Spectral domain optical coherence tomography, fundus autofluorescence, fluorangiography and indocyanine green angiography were evaluated. Results In total, 51 patients were included with a mean follow‐up of 30?months. The presence of the external limiting membrane ( ELM ) was a significant predictor for a favourable visual outcome 1?year after FMT ( OR ?=??0.30). Other significant predictive factors were the absence of intraretinal fluid ( OR ?=?0.28) and the mixed choroidal neovascularization type ( OR ?=??0.47), whereas nonresponders ( OR ?=?0.41) and fibrotic lesions ( OR ?=?0.35) were less likely to have a good visual function after surgery. Conclusion Full macular translocation ( FMT ), that permits to relocate the diseased macula onto an area of unaffected retinal pigment epithelial and choroid, can restore the anatomy and visual function in some patients with AMD when the outer retina layers are not irreversibly damaged. The presence of the ELM seems to be the most reliable factor in predicting the functional outcome.
机译：摘要目的，描述全黄斑易位（FMT）后视网膜形态的变化进行渗出性年龄相关的黄斑变性（AMD）并确定视觉结果的预测因素。方法选择从2008年12月到2013年7月到2013年7月的所有接受FMT的患者。除AMD的其他疾病的排除标准是FMT，年龄＆ 60？年，＆ 12？几个月的后续或没有可用的图像。评估光谱域光学相干断层扫描，眼底自发荧光，氟荧光和吲哚菁绿色血管造影。结果总计，51名患者均包含在30月30日的平均随访中。外部限制性膜（ELM）的存在是有利的视觉结果1？在FMT（或？= 0.30）之后的有利视觉结果1？。其他显着的预测因素是没有静脉内液（或α= 0.28）和混合脉络膜新生血管形成（或α=Δε0.47），而非反应者（或？=Δ0.41）和纤维化病变（或？= 0.35 ）手术后不太可能具有良好的视觉功能。结论全黄斑易位（FMT），允许将患病患者迁移到未受影响的视网膜颜料上皮和脉络膜区域上，可以在外视层层不可逆转地损坏时恢复一些AMD患者的解剖和视觉功能。榆树的存在似乎是预测功能结果中最可靠的因素。

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