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首页> 外文期刊>Acta ophthalmologica >Development and testing of a patient‐derived questionnaire for treatment of neovascular age‐related macular degeneration: dimensions of importance in treatment of neovascular age‐related macular degeneration
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Development and testing of a patient‐derived questionnaire for treatment of neovascular age‐related macular degeneration: dimensions of importance in treatment of neovascular age‐related macular degeneration

机译：用于治疗新生血管年龄相关性黄斑变性的患者衍生问卷的开发和测试：治疗新生血管年龄相关性黄斑变性的重要性

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Abstract Purpose Studies reporting on patient perspectives during treatment of neovascular age‐related macular degeneration ( nAMD ) are limited. Thus, the aim of this study was to develop and test psychometric performance of a patient‐derived questionnaire to capture important experiences during intravitreal treatment. Methods Patients ( n ?=?44) with at least 3‐month experience of intravitreal injection treatment for nAMD identified the dimensions of priority and also performed a weighting procedure to develop a score for comparison. The questionnaire comprised two versions: one focusing on the relative importance’ of the dimensions and one on the experience of the ‘management’ during treatment. The questionnaire was then tested for psychometric performance in a longitudinal design in newly diagnosed patients at baseline ( n ?=?197), after three ( n ?=?184) and six ( n ?=?150) months of treatment. Results Of the 15 included dimensions, the following were most frequently reported: ‘receive treatment to preserve vision’, ‘information’, ‘waiting time’, ‘trust’ and ‘accommodating staff. The psychometric testing showed moderate reliability (intraclass correlation coefficient: 0.65–0.67) for the two versions and high level of face validity (8.3). The dimensions, ‘preserving vision’, ‘early access to treatment’, ‘pain relief’, ‘information about the treatment/diagnosis’ and ‘visual aids’ were consistently reported higher in ‘importance’ than in ‘management’, at both 3 and 6?months, indicating a potential for improvement in clinical practice for these dimensions. Conclusion This study provides a brief patient‐derived questionnaire, expressed with a score with good psychometric performance that can be used for monitoring during intravitreal injection treatment of nAMD patients.
机译：摘要目的研究报告在治疗新生血管时代相关黄斑变性（NAMD）期间的患者观点是有限的。因此，本研究的目的是开发和测试患者衍生的问卷的心理测量性能，以捕获玻璃体内治疗期间的重要经验。方法患者（n？=Δ44），NAMD的玻璃体内注射处理至少为3个月的体验，确定了优先级的尺寸，并且还进行了加权程序以开发比较的分数。调查问卷由两个版本组成：一个重点关注尺寸的相对重要性，以及在治疗期间“管理”的体验。然后在新诊断的基线患者的纵向设计中测试了调查问卷的心理表现，在基线（n？= 197），三次（n？=α184）和六个（n？= 150）个月的治疗中。 15款包括尺寸的结果，以下最常报告：“接受待存愿景”，“信息”，“等待时间”，“信任”和“容纳员工”。心动测量测试显示了两种版本和高水平的面部有效性（8.3）的中等可靠性（脑内相关系数：0.65-0.67）。尺寸，“保存愿景”，“早期获得治疗”，“疼痛缓解”，“关于治疗/诊断”和“视觉助剂”的信息始终如一地报告在“重要性”中，而不是“管理”，两者在3中和6个月，表明这些尺寸的临床实践有所改善。结论本研究提供了一个简短的患者衍生的问卷，表达了良好的心理表现，可用于在NAMD患者的玻璃体内注射治疗期间进行监测。

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