Inverted formins: A subfamily of atypical formins

Hegsted Anna; Yingling Curtis V.; Pruyne David

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Inverted formins: A subfamily of atypical formins

机译：倒形状：非典型格式的亚家族

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Abstract Formins are a family of regulators of actin and microtubule dynamics that are present in almost all eukaryotes. These proteins are involved in many cellular processes, including cytokinesis, stress fiber formation, and cell polarization. Here we review one subfamily of formins, the inverted formins. Inverted formins as a group break several formin stereotypes, having atypical biochemical properties and domain organization, and they have been linked to kidney disease and neuropathy in humans. In this review, we will explore recent research on members of the inverted formin sub‐family in mammals, zebrafish, fruit flies, and worms.

机译：摘要Formins是肌动蛋白和微管动态的一个调节因子，几乎所有真核生物都存在。这些蛋白质涉及许多细胞过程，包括细胞因子，应激纤维形成和细胞偏振。在这里，我们审查了一个胎儿的胎选，倒置。作为群体的倒形状破坏了几种甲状腺素刻板印象，具有非典型生化特性和结构域组织，它们与人类的肾病和神经病变有关。在这篇综述中，我们将探讨最近关于哺乳动物，斑马鱼，果蝇和蠕虫的倒置素子家庭成员的研究。

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来源
《Cytoskeleton》 |2017年第11期|共15页
作者
Hegsted Anna; Yingling Curtis V.; Pruyne David;
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作者单位

Department of Cell and Developmental BiologySUNY Upstate Medical UniversitySyracuse New York 13210;

Department of Cell and Developmental BiologySUNY Upstate Medical UniversitySyracuse New York 13210;

Department of Cell and Developmental BiologySUNY Upstate Medical UniversitySyracuse New York 13210;

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原文格式 PDF
正文语种 eng
中图分类细胞生物学;
关键词
actin; Charcot‐Marie‐Tooth disease; FHDC1; focal segmental glomerulosclerosis; INF2;

机译：actin;charcot-marie-tooth疾病;fhdc1;焦点节段性肾小球粥样硬化;INF2;

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1. Inverted formins: A subfamily of atypical formins [J] . Hegsted Anna, Yingling Curtis V., Pruyne David Cytoskeleton . 2017,第11期

机译：倒形状：非典型格式的亚家族
2. Inverted Formin 2 Regulates Actin Dynamics by Antagonizing Rho/Diaphanous-related Formin Signaling [J] . Hua Sun, Johannes Schlondorff, Henry N. Higgs, Journal of the American Society of Nephrology: JASN . 2013,第6期

机译：反向的Formin 2通过拮抗Rho / Diaphanous相关的Formin信号传导来调节肌动蛋白动力学。
3. Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2) [J] . Hua Sun, Johannes S. Schlondorff, Elizabeth J. Brown, Proceedings of the National Academy of Sciences of the United States of America . 2011,第7期

机译：mDia formins的Rho激活是通过与反向的formin 2（INF2）相互作用来调节的。
4. Understanding the Interaction of Human Formin Binding Protein 4 with Formin FMN1 [C] . Amit Das, Simanti Bhattacharya, Angshuman Bagchi, International Conference on Information Systems Design and Intelligence Applications . 2015

机译：用甲状腺FMN1了解人素结合蛋白4的相互作用
5. Regulation of Inverted Formin-1 (INF1) by Microtubule-Affinity Regulating Kinase 2 (MARK2). [D] . Kulacz, Wojciech. 2012

机译：通过微管亲和力调节激酶2（MARK2）调节反向Formin-1（INF1）。
6. Inverted Formins: a Sub-Family of Atypical Formins [O] . Anna Hegsted, Curtis V. Yingling, David Pruyne -1

机译：反向福尔摩斯：非典型福尔摩斯的一个子家族
7. Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2) [O] . Sun, Hua, Schlondorff, Johannes S., Brown, Elizabeth J., 2011

机译：mDia formins的Rho激活是通过与倒置的formin 2（INF2）相互作用来调节的。

Inverted formins: A subfamily of atypical formins

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