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A man with abdominal pain and eosinophilia : tissue is the issue

机译:一个腹痛和嗜酸性粒细胞的男人:组织是问题

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摘要

A 24-year-old male presented with abdominal pain, postprandial vomiting and weight loss. Lab results showed an elevated serum eosinophil count and CT-scan demonstrated a thickened antral, duodenal and jejunal wall. Repetitive endoscopic mucosal biopsies were normal. Work-up of eosinophilia-associated gastro-intestinal disorders excluded secondary causes. Bone marrow showed an elevated eosinophil count without arguments for a primary hypereosinophilic syndrome. Endoscopic ultrasound-guided fine needle biopsy detected a strongly elevated number of eosinophils in the muscularis layer of the duodenum. The diagnosis of muscularis-predominant eosinophilic gastroenteritis together with a secondary hypereosinophilic syndrome was made. The patient was started on steroids and all symptoms vanished within a few days.
机译:一名24岁的男性患有腹痛,餐后呕吐和减肥。 实验室结果表明,血清嗜酸性粒细胞计数升高,CT扫描演示了一种增厚的antral,十二指肠和jejunal墙壁。 重复的内窥镜粘膜活组织检查是正常的。 嗜酸性粒细胞相关的胃肠疾病的锻炼排除了二次原因。 骨髓显示嗜酸性粒细胞计数升高,没有争论原发性低渗综合征。 内窥镜超声引导的细针活检检测到十二指肠的肌肉层中强烈升高的嗜酸性粒细胞。 制备了肌肉肌肉肌肉血液粒细胞肠炎的诊断与继发性低渗综合征。 患者在类固醇上开始,所有症状都在几天内消失了。

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