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首页> 外文期刊>Acta gastro-enterologica Belgica >Comparison between abdominal fat measured by CT and anthropometric indices as prediction factors for mortality and morbidity after colorectal surgery
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Comparison between abdominal fat measured by CT and anthropometric indices as prediction factors for mortality and morbidity after colorectal surgery

机译：CT和人体测量指数测量的腹部脂肪与结直肠手术后死亡率和发病率的预测因素

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Aim : This study aims to determine which anthropometric (body mass index (BMT), waist-hip-ratio (WHR) and waist-to-height ratio (WHtR)) and radiological (visceral fat area (VFA) measured by CT scan) measurements of adiposity correlated better with postoperative outcome of colorectal cancer (CRC) surgery. We also assessed which of these measurements best predicted overall survival (OS) and disease-free survival (DFS).Methods : Data from 90 consecutive Caucasian CRC patients who underwent surgery for colorectal cancer between 2010 and 2011 with a median follow-up of 53.25 months were analysed. The correlations of different adiposity measurements and postoperative outcomes were determined using logistic regression models and multivariate analyses.Results : Higher WHtR (p = 0.007) and VFA (p = 0.01) significantly increased the risk of overall morbidity, especially of Clavien-Dindo HI or IV. The WHtR correlated best with VFA (p < 0.0001), which is considered the gold standard for measuring visceral fat, whereas BMI (p = 0.15) was not a good predictor of postoperative morbidity.Multivariate analyses showed consistently significant results for postoperative complications for VFA in combination with all of the other variables analysed and for WHtR, confirming that VFA and WHtR were reliable independent prognostic factors of morbidity. VFA had a significant effect on OS (p = 0.012) but did not correlate with DFS (p = 0.51).Conclusions : Both VFA and WHtR independently provided predictive data for potential postoperative complications after CRC surgery. In case CT scan is used for diagnostic purposes, VFA should be used in routine clinical practice. (Acta gastroenterol. belg., 2018, 81, 477-483).
机译：目的：本研究旨在确定由CT扫描测量的哪个人体测量（体重指数（BMT），腰臀比（WHR）和腰部到高度（WHTR））和放射线（内脏脂肪区域（VFA））用结肠直肠癌（CRC）手术的术后结果更好地相关的肥胖相关。我们还评估了哪些测量最佳预测总体存活（OS）和无病生存（DFS）。方法：来自2010年和2011年之间的连续癌症的90名连续白种人CRC患者的数据，其中包括53.25的中位随访分析了几个月。使用逻辑回归模型和多变量分析确定不同肥胖测量和术后结果的相关性。结果：更高的WHTR（P = 0.007）和VFA（P = 0.01）显着提高了整体发病率的风险，特别是Clavien-Dindo Hi或IV。 WHTR与VFA（P <0.0001）相关，这被认为是测量内脏脂肪的金标准，而BMI（P = 0.15）不是术后发病率的良好预测因子.. VFA的术后并发症表现出始终如一的显着成果对VFA的术后并发症表现出始终如一结合分析的所有其他变量和用于WHTR，确认VFA和WHTR是可靠的性发病率的独立预后因素。 VFA对OS有显着影响（p = 0.012），但与DFS没有相关（p = 0.51）.CRC手术后，VFA和WHTR独立地提供了用于潜在术后并发症的预测数据。如果CT扫描用于诊断目的，VFA应用于常规临床实践。 （Acta Gastroenterol。Belg。，2018,81,477-483）。

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