...
首页> 外文期刊>Acta Oto-Laryngologica >Periodontal status at diagnosis predicts non-disease-specific survival in a geographically defined cohort of patients with oropharynx squamous cell carcinoma
【24h】

Periodontal status at diagnosis predicts non-disease-specific survival in a geographically defined cohort of patients with oropharynx squamous cell carcinoma

机译:诊断时的牙周病患者在地理上定义的患有口腔鳞状细胞癌的患者的地理上定义的群体中预测了非疾病特异性的存活

获取原文
获取原文并翻译 | 示例
           

摘要

Background: The aim of this study was to examine periodontal status with a time-efficient screening method from a cohort of newly diagnosed oropharynx squamous cell carcinoma (OPSCC) patients and to study to what extent dental disease level predicted survival. Aims/objective: Can measuring level of dental pathology based on a blind investigation of a routine orthopantogram (OPG) obtained during diagnostic workup reveal prognostic information? Materials and methods: We included 97 patients diagnosed between 2003 and 2010. Radiographic alveolar bone loss was measured. At least 4 mm bone loss from cement-enamel junction on at least two teeth was registered as periodontal pathology. The number of missing and filled teeth (MFT), residual roots and apical radiolucencies were noted. Clinical data were determined through hospital patient records. Results: The horizontal bone loss discriminated between hr-HPV(+) versus hr-HPV(-) status, but secondary to age and smoking history at diagnosis. Vertical and horizontal bone loss predicted survival directly, and adjusted by gender, patient, smoking history, TN stage and hr-HPV tumor infection at diagnosis. Conclusions: Degree of periodontal OPG pathology at the time of OPSCC diagnosis to some extent predicted hr-HPV infection, but predicted non-disease-specific long-term survival. Significance: Degree of periodontal OPG pathology at diagnosis predicts prognosis.
机译:背景:本研究的目的是通过从新诊断的胃痛性鳞状细胞癌(OPSCC)患者的群组中的时间有效的筛选方法来研究牙周地位,并研究牙科疾病水平预测生存的程度。目的/目的:可以根据诊断后处理期间获得的常规正交图(OPG)的盲目调查测量牙科病理水平揭示预后信息吗?材料和方法:我们包括2003年至2010年诊断的97例患者。测量了射线照相肺泡骨损失。至少两颗牙齿上的水泥搪瓷结至少4mm骨损失被注册为牙周病理学。注意到缺失和填充的牙齿(MFT),残留根和顶部辐射的数量。通过医院患者记录确定临床资料。结果:HR-HPV(+)与HR-HPV( - )状态之间区别的水平骨损失,但诊断时继发于年龄和吸烟。垂直和水平骨质损失预测直接存活,并通过性别,患者,吸烟病史,TN阶段和HR-HPV肿瘤感染进行调整。结论:在OPSCC诊断时期牙周病病理程度在一定程度上预测HR-HPV感染,但预测了特异性的非疾病性长期存活。意义:诊断牙周病病理学的程度预测预后。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号