Visualizing protoporphyrin IX formation in the dura tail of meningiomas by mass spectrometry imaging

Brokinkel Benjamin; Kroeger Sabrina; Senner Volker; Jeibmann Astrid; Karst Uwe; Stummer Walter

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Visualizing protoporphyrin IX formation in the dura tail of meningiomas by mass spectrometry imaging

机译：通过质谱成像在脑膜炎癌症的Dura尾部可视化原始卟啉IX

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The advantages of 5-aminolevulinacid (5-ALA)-induced fluorescence-guided surgery in meningiomas are increasingly discussed. In this context, despite detectable tumor tissue in histopathologial analyses, no fluorescence was shown at the dura tail using the standard operating microscope. Thus, 5-ALA metabolism in this surgically important site remains unknown but needs to be elucidated when further evaluating indications of fluorescence-guided surgery in meningiomas.

机译：越来越多地讨论5-氨基乙酰氨基丙酸（5 Ala）诱导荧光导向手术的优点。在这种情况下，尽管在组织病理学分析中具有可检测的肿瘤组织，但是使用标准操作显微镜在Dura尾部显示荧光。因此，在这种外科重要部位中的5 Ala代谢仍然未知，但是当进一步评估脑膜瘤中的荧光引导手术的指示时需要阐明。

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来源
《Acta Neurochirurgica》 |2018年第7期|共5页
作者
Brokinkel Benjamin; Kroeger Sabrina; Senner Volker; Jeibmann Astrid; Karst Uwe; Stummer Walter;
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作者单位

Univ Hosp Munster Dept Neurosurg Albert Schweitzer Campus 1 Bldg A1 D-48149 Munster North Rhine;

Univ Munster Inst Inorgan &

Analyt Chem Munster North Rhine Wes Germany;

Univ Hosp Inst Neuropathol Munster North Rhine Wes Germany;

Univ Hosp Inst Neuropathol Munster North Rhine Wes Germany;

Univ Munster Inst Inorgan &

Analyt Chem Munster North Rhine Wes Germany;

Univ Hosp Munster Dept Neurosurg Albert Schweitzer Campus 1 Bldg A1 D-48149 Munster North Rhine;

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原文格式 PDF
正文语种 eng
中图分类头部及神经外科学;
关键词
5-aminolevulinic acid; Fluorescence; Meningioma; Resection; MALDI-MS imaging;

机译：5-氨基纤维素酸;荧光;脑膜瘤;切除;MALDI-MS成像;

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专利

1. Visualizing protoporphyrin IX formation in the dura tail of meningiomas by mass spectrometry imaging [J] . Brokinkel Benjamin, Kroeger Sabrina, Senner Volker, Acta Neurochirurgica . 2018,第7期

机译：通过质谱成像在脑膜炎癌症的Dura尾部可视化原始卟啉IX
2. Nitric oxide inhibits the formation of zinc protoporphyrin IX and protoporphyrin IX [J] . Jun-ichi Wakamatsu, Nobutaka Hayashi, Takanori Nishimura, Meat Science . 2009,第1期

机译：一氧化氮抑制锌原卟啉IX和原卟啉IX的形成
3. Can Excision of Meningiomas Be Limited to Resection of Tumor and Radiologically Abnormal Dura Mater? Neuronavigation-Guided Biopsies of Dural Tail and Seemingly Normal Dura Mater, with a Review of the Literature [J] . Slot K. Mariam, Verbaan Dagmar, Uitdehaag Bernard M. J., World neurosurgery . 2014,第6期

机译：脑膜瘤的切除可以局限于切除肿瘤和放射学异常的硬脑膜吗？硬脑膜尾神经和看似正常的硬脑膜的神经导航引导活检，并有文献复习
4. NITRIC OXIDE INHIBITS THE FORMATION OF ZINC PROTOPORPHYRIN IX AND PROTOPORPHYRIN IX [C] . Zhao Li, rnZhang Ling, rnWang Feng Proceedings of 53rd International Congress of Meat Science and Technology . 2007

机译：一氧化氮抑制锌原卟啉IX和原卟啉IX的形成
5. Single molecule imaging and spectroscopy of protoporphyrin IX and its metal derivatives [D] . Hu, Yi 2011

机译：原卟啉IX及其金属衍生物的单分子成像和光谱学
6. Estimation of Brain Deformation for Volumetric Image Updating in Protoporphyrin IX Fluorescence-Guided Resection [O] . Pablo A. Valdés, Xiaoyao Fan, Songbai Ji, -1

机译：原卟啉IX荧光引导下切除术中体积图像更新的脑变形估计。
7. Formation of Zinc Protoporphyrin IX and Protoporphyrin IX from Oxymyoglobin in Porcine Heart Mitochondria [O] . Hiroya ISHIKAWA, Taiki KAWABUCHI, Yuriko KAWAKAMI, 2007

机译：从蛇心肌细胞杂烩中形成氧化杂蛋白的锌原卟啉IX和原子卟啉IX

Visualizing protoporphyrin IX formation in the dura tail of meningiomas by mass spectrometry imaging

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