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How reliable is renal ultrasound to measure renal length and volume in patients with chronic kidney disease compared with magnetic resonance imaging?

机译:与磁共振成像相比,肾超声测量慢性肾病患者的肾脏长度和体积的可靠性如何?

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Background Renal length, volume, and parenchymal thickness are important clinical parameters, yet data concerning the accuracy and reproducibility of ultrasound (US)-based renal length and volume assessment in patients with chronic kidney disease (CKD) are scarce. Purpose To establish whether renal length, volume, and parenchymal thickness can be reliably measured with renal US in patients with CKD. Material and Methods All participants underwent renal US, immediately followed by 3-T magnetic resonance imaging (MRI). Renal length, width, transverse diameter, and parenchyma thickness were measured with both methods; renal volume was calculated using the ellipsoid formula. A total of 45 patients with CKD (eGFR [mean +/- SD] 57.4 +/- 4.4 mL/min/1.73 m(2)) and 46 participants without CKD (eGFR 97.0 +/- 2.4 mL/min/1.73 m(2)) were included. Results US-measured renal length correlated strongly with MRI-measured renal length in no-CKD patients (Spearman's r = 0.83 and 0.85 for the right and left kidney, respectively; P < 0.005) and CKD patients (r = 0.89 and 0.92 for the right and left kidney, respectively; P < 0.005). There was a significant but weaker correlation between MRI- and US-measured right and left renal volume (r = 0.72, P < 0.005) in no-CKD (r = 0.74 and r = 0.72, respectively; for both: P < 0.005) and CKD patients (r = 0.83 and 0.85, P < 0.005). Weak to moderate correlations were found for parenchyma thickness for the right (CKD group: r = 0.29, no-CKD: r = 0.23; for both: P < 0.05) and left kidney (CKD: r = 0.52, no-CKD group: r = 0.37, P < 0.05). Both intra-observer (Pearson's correlations of 0.82 for the right and 0.89 for the left kidney) and inter-observer (Lin's correlation coefficient of 0.90 for the right and 0.82 for the left kidney) reproducibility of US-assessed renal length was high. Conclusions US-based assessment of renal length in CKD patients is comparable to MRI measures. Both intra- and inter-observer reproducibility of US-assessed renal length in CKD patients are high. Measurements of US renal volume and parenchymal thickness should, however, be interpreted with caution.
机译:背景技术肾脏长度,体积和实质厚度是重要的临床参数,然而,慢性肾病(CKD)患者的超声(美国)基于肾脏长度和体积评估的准确性和再现性的数据是稀缺的。目的,建立肾脏长度,体积和实质厚度是否可以通过CKD患者用肾脏可靠地测量。材料和方法所有参与者都接受了肾脏我们,紧接着是3-T磁共振成像(MRI)。用两种方法测量肾脏长度,宽度,横向直径和实质厚度;使用椭圆形配方计算肾体积。共有45例CKD患者(EGFR [平均值+/- SD] 57.4 +/- 4.4ml / min / 1.73 m(2))和46名没有CKD的参与者(EGFR 97.0 +/- 2.4 ml / min / 1.73米( 2)包括。结果我们测量的肾脏长度与No-CKD患者的MRI测量肾脏长度强烈相关(Spearman的r = 0.83和0.85分别用于右肾和左肾)和CKD患者(R = 0.89和0.92右肾脏分别; p <0.005)。 MRI-和美国测量的右侧和左肾体积(r = 0.72,p <0.005)分别存在显着但较弱的相关性(r = 0.74和r = 0.72;两者:p <0.005)和CKD患者(r = 0.83和0.85,p <0.005)。发现对右侧的实质厚度(CKD组:r = 0.29,NO-CKD:r = 0.23;两者:P <0.05)和左肾(CKD:r = 0.52,NO-CKD组: r = 0.37,p <0.05)。观察者内部(Pearson的相关性(Pearson为右肾的0.82和0.89)和观察者间(Lin的相关系数为0.90,左肾的0.82)美国评估肾脏长度的再现性高。结论CKD患者中肾脏长度的基于美国的评估与MRI措施相当。在CKD患者中,美国评估的肾脏长度的口腔内和观察者间的再现性都很高。然而,美国肾脏体积和实质厚度的测量应谨慎解释。

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