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Patterns of initially overlooked recurrence of peritoneal lesions in patients with advanced ovarian cancer on postoperative multi-detector row CT

机译:在术后多探测器行CT上晚期卵巢癌患者初始忽略腹膜病变复发的模式

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Background In order to obtain timely treatment, the early detection of recurrent ovarian cancer is essential. Despite technical advances in multi-detector row computed tomography (MDCT), low sensitivity of CT for recurrence has not been improved much due to its poor soft tissue discrimination. Purpose The aim of this study is to describe patterns of erroneous postoperative MDCT interpretation of recurred peritoneal lesions in patients with advanced ovarian cancer (AOC). Material and methods Between 2011 and 2018, we reviewed postoperative follow-up positron emission tomography (PET)/CT images of 240 patients with suspected recurrence based on the images and history of initially diagnosed AOC (International Federation of Gynecology and Obstetrics stage IIIC-IV) who had undergone primary cytoreduction. With awareness of recurred location, we re-evaluated MDCT images taken right before the recurrence was detected on PET/CT and categorized these cases as either the absence of a lesion or the presence of a lesion (missed case). We performed region-based comparisons of these missed cases according to predefined peritoneal locations. Results Re-evaluation of follow-up MDCT images revealed that 46.9% (105/224) of recurrent lesions were missed. Through region-based analysis, the most commonly missed site was the pelvic cavity (19.0%, 20/105), followed by the porta hepatis (15.2%, 16/105) and the para-aortic/aortocaval lymphadenopathy (13.3%, 14/105). Conclusion Radiologists should be concerned about these frequently overlooked regions in postoperative follow-up MDCT images when potential risks are identi?ed. Familiarity with these imaging features may aid in the detection of recurrence and facilitate appropriate management.
机译:背景技术为了获得及时治疗,早期检测反复性卵巢癌是必不可少的。尽管在多探测器行计算断层扫描(MDCT)中存在技术进步,但由于软组织辨别差,CT对复发的低灵敏度尚未得到改善。目的本研究的目的是描述先进卵巢癌(AOC)患者重复腹膜病变的错误术后MDCT解释模式。 2011年和2018年的材料和方法,我们审查了术后随访的正电子发射断层扫描(PET)/ CT图像的240例疑似复发患者,基于最初诊断的AOC的图像和历史(国际妇科和妇产科IIIC-IV联合会)谁经历过初级细胞统治。具有认证位置的认识,我们重新评估在检测到在PET / CT上检测到复发前的MDCT图像,并将这些病例分类为不存在病变或存在病变(错过案例)。根据预定义的腹膜地点,我们对这些错过病例进行了基于地区的比较。结果再次评估后续MDCT图像显示,错过了46.9%(105/224)的复发病变。通过基于地区的分析,最常见的网站是盆腔腔(19.0%,20/105),其次是Porta肝(15.2%,16/105)和帕拉主动脉/主动脉瘤淋巴结病(13.3%,14 / 105)。结论放射科医师应该在潜在的风险识别时术后随访MDCT图像中的这些经常被忽视的区域。熟悉这些成像特征可能有助于检测到复发并促进适当的管理。

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