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首页> 外文期刊>Acta Radiologica >Intra- and inter-observer agreement in the visual interpretation of interim 18F-FDG PET/CT in malignant lymphoma: influence of clinical information
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Intra- and inter-observer agreement in the visual interpretation of interim 18F-FDG PET/CT in malignant lymphoma: influence of clinical information

机译：在恶性淋巴瘤中临时18F-FDG PET / CT的视觉解释中的内部和观察者间协议：临床信息的影响

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Background Interim PET/CT is widely performed in lymphoma patients in clinical practice and clinical trials. Visual assessment using a 5-point scale is proposed for PET/CT interpretation, but intra- and inter-observer variation is not fully investigated. Purpose To investigate intra- and inter-observer variations in the reporting of interim positron emission tomography/computed tomography (PET/CT) in lymphoma patients, and the influence of clinical information on the interpretation. Material and Methods Three expert readers from different institutions interpreted interim PET/CT images of 42 consecutive patients with malignant lymphoma twice, with and without clinical information. The intra- and inter-observer agreements were calculated using the kappa statistic on a patient and a region basis. Results On a patient basis, intra-observer agreement, inter-observer agreement without information, and inter-observer agreement with information were within the ranges 0.48–0.62, 0.51–0.62, and 0.42–0.76, respectively. In the evaluation of lymph nodes, intra-observer agreement, inter-observer agreement without information, and inter-observer agreement with information were within the ranges 0.78–0.92, 0.80–0.82, and 0.77–0.83, respectively. Observer agreements were in almost perfect to substantial agreement categories for most lymphatic organs, but were generally low for the other organs. Conclusion The intra- and inter-observer agreements in evaluating interim PET/CT were relatively low for extranodal lesions, but they were substantial to almost perfect when interpreting nodal regions in malignant lymphoma, irrespective of the provision of clinical information, although memory at the first interpretation might have affected the intra-observer results.
机译：背景技术在临床实践和临床试验中广泛地进行淋巴瘤患者中的临时宠物/ CT。提出了使用5分尺度的视觉评估，用于PET / CT解释，但没有完全调查和观察者间的异常变异。目的是调查淋巴瘤患者临时正电子发射断层扫描/计算断层扫描（PET / CT）的报告中的观察者和观察者间变化以及临床信息对解释的影响。材料与方法来自不同机构的三位专家读者解释了42例连续42例恶性淋巴瘤患者的临时宠物/ CT图像两次，有和没有临床信息。在患者和区域基础上使用Kappa统计来计算出境和观察员间协议。结果在患者基础上，观察员内达成协议，没有信息的观察员间协议以及与信息间的观察员协议分别在0.48-0.62,0.51-0.62和0.42-0.76范围内。在评估淋巴结的评估中，观察员内或没有信息的观察员协议，以及观察员协议的信息分别在0.78-0.92,0.80-0.82和0.77-0.83内。观察员协议几乎完美地对大多数淋巴器官的大量协议类别，但对其他器官通常很低。结论，对临时宠物/ CT的临时和观察员间协议对于外侧病变相对较低，但在解释恶性淋巴瘤中的节点区域时，它们几乎完善，而且无论提供临床信息，虽然第一次记忆解释可能影响了观察室内的结果。

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