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Does the menstrual cycle affect the multimodal ultrasound tomography?

机译:月经周期是否会影响多模式超声波断层扫描?

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Background Multimodal ultrasound tomography (MUT) is a promising new three-dimensional imaging technology for breast cancer detection without ionizing radiation or need for tissue compression. It offers an automatic scan of the pendulant whole breast. Purpose As breast tissue properties are affected by the menstrual cycle (MC), we examined whether there is an objective difference in the refractivity and attenuation images obtained via MUT at different phases of the menstrual cycle. Material and Methods Thirteen asymptomatic volunteers (age range = 27-44 years) with a regular MC were scanned once weekly for four weeks. Attenuation and refractivity images of the breast coronal slices obtained via MUT are calibrated against precisely controlled water-through values of the ultrasound waves. The average of attenuation and refractivity values measured in the MUT images were calculated for each volunteer every week. Results During the MC, the weekly averages of the refractivity images for all volunteers were -0.650% (week 1), -0.585% (week 2), -0.692% (week 3), and -0.628% (week 4), and the corresponding attenuation weekly averages were 1.712 dB/cm, 1.635 dB/cm, 1.673 dB/cm, and 1.653 dB/cm. There were no statistically significant changes during MC. Conclusion Although there are biological changes in breast tissue properties during the MC, we did not observe statistically significant changes in the average values of MUT refractivity and attenuation images in each breast for different weeks of the MC. This finding implies that the diagnostic accuracy of the MUT may not be affected by the timing of the scan during the MC.
机译:背景技术多峰超声断层扫描(MUT)是一种有希望的新的三维成像技术,用于乳腺癌检测,而不需要电离辐射或需要组织压缩。它提供了全乳房的自动扫描。目的作为乳房组织特性受月经(MC)的影响,我们检查了是否在月经周期的不同阶段通过MUT获得的折射率和衰减图像中是否存在客观差异。材料和方法通过常规MC的十三个无症状志愿者(年龄范围= 27-44岁)每周扫描一次四周。通过MUT获得的乳腺冠状切片的衰减和折射图像被校准,以防止超声波的精确控制的水值。每周为每个志愿者计算在MUT图像中测量的衰减和折射率值的平均值。结果在MC期间,所有志愿者的折射率图像的每周平均值为-0.650%(第1周),-0.585%(第2周),-0.692%(第3周),和-0.628%(第4周),和相应的衰减每周平均值为1.712 db / cm,1.635 db / cm,1.673 db / cm,1.653 db / cm。 MC期间没有统计学意义的变化。结论虽然MC期间乳腺组织特性存在生物学变化,但我们在MC的不同周内,我们没有观察每个乳房中mut折射率和衰减图像的平均值的统计学显着变化。该发现意味着MUT的诊断准确性可能不会受到MC期间扫描的定时的影响。

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