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首页> 外文期刊>Advances in Digestive Medicine >Unusual subcutaneous and choroidal metastases from esophageal squamous cell carcinoma denote a poor prognosis: A case report and literature review
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Unusual subcutaneous and choroidal metastases from esophageal squamous cell carcinoma denote a poor prognosis: A case report and literature review

机译：食管鳞状细胞癌的不寻常的皮下和脉络膜转移表示预后差：案例报告和文献综述

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Esophageal squamous cell carcinoma (ESCC) is a devastating disease, generally diagnosed at an advanced stage. Skin metastasis is rare, and choroidal metastases are extremely rare. Herein, we report a case of a 47-year-old habitual smoker and drinker who presented with progressive dysphagia, weight loss, and multiple enlarged tumors over his trunk and limbs for 3 months. Upper endoscopy revealed an ulcerative esophageal mass, and pathology confirmed moderately differentiated SCC. Fluorodeoxyglucose-positron emission tomography/computed tomography revealed high uptake in the esophageal mass, bone, and subcutaneous lesions. Incisional biopsy of the right thigh tumor indicated metastatic SCC. Accordingly, the patient received palliative chemotherapy and mediastinal radiotherapy. Two weeks later, he experienced partial right visual field loss. Imaging findings suggested choroidal metastasis. Although the skin lesions shrank after treatment, the patient's health quickly deteriorated and he died of severe pneumonia 3 months later. To our knowledge, this is the first report of ESCC with simultaneous subcutaneous and ocular metastasis. Cutaneous and ocular metastases secondary to ESCC are extremely rare; both suggest cancer dissemination and imply an ominous prognosis. Careful physical examination and high awareness are required during follow-up.
机译：食管鳞状细胞癌（ESCC）是一种毁灭性的疾病，通常被诊断为晚期。皮肤转移是罕见的，脉络膜转移非常罕见。在此，我们举报了一个47岁的习惯吸烟者和饮酒者，他们呈现出渐进的吞咽，减肥和他的躯干和四肢向肢体的多发性肿瘤3个月。上内窥镜检查显示出溃疡性食管质量，并且病理学确认了中度分化的SCC。氟脱氧葡萄糖 - 正电子发射断层扫描/计算机断层扫描显示出在食管质量，骨骼和皮下病变中的高吸收。右大腿肿瘤的切口活检表明转移性SCC。因此，患者接受了姑息化化疗和纵隔放射治疗。两周后，他经历了部分正确的视野损失。成像结果表明脉络膜转移。虽然治疗后皮肤病变萎缩，但患者的健康迅速恶化，他3个月后他死于严重的肺炎。据我们所知，这是ESCC具有同时皮下和眼部转移的第一报告。继发于ESCC的皮肤和眼转移极少;两者都表明癌症传播，暗示了不祥的预后。在随访期间需要仔细体检和高意识。

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