...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Crystal growth & design >ATR-FTIR for Determining Optimal Cooling Curves for Batch Crystallization of Succinic Acid
【24h】

ATR-FTIR for Determining Optimal Cooling Curves for Batch Crystallization of Succinic Acid

机译：ATR-FTIR用于确定琥珀酸分批结晶的最佳冷却曲线

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The temperature profile applied during batch cooling crystallization affects the supersaturation level, which in turn affects the crystal size distribution. It is possible, in principle, to calculate the optimal cooling profile; however, the nucleation and growth kinetics are rarely known to the degree of accuracy necessary for this calculation. The current study demonstrates an alternative approach to determination of the optimal cooling profile without any prior knowledge of kinetic data or subsequent modeling. An attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectrometer was used to monitor the supersaturation level during batch cooling crystallization. The ATR-FTIR was interfaced to a LABMAX automatic reactor system that was used in a feedback mode to control the cooling rate so that the supersaturation level remained close to the solubility throughout the cooling process. The resulting temperature profile corresponds to the optimal operating conditions for the maximum in the mean crystal size.
机译：在分批冷却结晶过程中施加的温度分布会影响过饱和度，进而影响晶体尺寸分布。原则上可以计算出最佳的冷却曲线。但是，成核和生长动力学很少达到计算所需的精确度。当前的研究表明，无需任何动力学数据或后续建模的先验知识即可确定最佳冷却曲线的替代方法。使用衰减的全反射傅里叶变换红外（ATR-FTIR）光谱仪监测间歇冷却结晶过程中的过饱和水平。 ATR-FTIR连接到LABMAX自动反应器系统，该系统以反馈模式使用以控制冷却速率，从而使过饱和度在整个冷却过程中保持接近溶解度。所得的温度曲线对应于最大晶体平均尺寸的最佳操作条件。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号