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首页> 外文期刊>Advances in Animal Biosciences >Genetic variability of the major histocompatibility complex (MHC) class II (DRB3) in South African and Namibian beef cattle breeds
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Genetic variability of the major histocompatibility complex (MHC) class II (DRB3) in South African and Namibian beef cattle breeds

机译：南非和纳米比亚牛肉品种主要组织相容性复合体（MHC）二级（MHC）二级（DRB3）的遗传变异

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摘要

The major histocompatibility complex region has been implicated in explaining some of the variation observed in adaptability and tick susceptibility of cattle. The bovine leukocyte antigen region of 192 cattle representing indigenous, composite and exotic breeds used in commercial beef production in Namibia and South Africa was investigated using four microsatellite markers. Ticks counted under the tail were taken as an indicator of tick susceptibility. Tick scores of all but one population was low (11 to 20 ticks), with only the South African Bonsmara population having an average score of 31 to 40 ticks per animal. The observed variation based on four microsatellite markers ranged from 5.5 alleles in Namibian Afrikaner to 7.7 alleles in South African Nguni and Bonsmara cattle. Unbiased heterozygosity values ranged from 0.66 (Namibian Afrikaner) to 0.76 (South African Bonsmara). Structure analyses grouped the five populations into three indistinct clusters with limited genetic variation between thepopulations.
机译：主要的组织相容性复杂区域涉及说明在牛的适应性和蜱溶胀性中观察到的一些变化。使用四种微卫星标记研究了纳米比亚和南非商业牛肉生产的土着，复合材料和异国情调的192条牛的牛白细胞抗原区。在尾部计算的蜱被视为蜱易感性的指标。勾选所有人，除了一个人口较低（11至20次蜱），只有南非盆景人口，平均得分为每只动物31至40次。观察到的基于四个微卫星标记的变化范围从纳米比亚氟丙烷的5.5等位基因到7.7南非Nguni和Bonsmara牛的等位基因。无偏见的杂合性值范围为0.66（纳米比亚氟丙烷料）至0.76（南非盆景）。结构分析将五个群体分为三个模糊簇，具有有限的遗传变异之间的遗传变异。

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