Tetraphenylborate Salt of Atropine (R): Synthesis and X-ray Structure of Tetraphenyl-lambda(4)-borane, (1R,3r,5S,8s)-3-((3-Hydroxy-2-phenylpropanoyl)oxy)-8-methyl-8-azabicyclo[3.2.1]octan-8-ium Salt

Mostafa G. A. E.; Ghabbour H. A.; Abdel-Aziz H. A.

首页> 外文期刊>Crystallography reports >Tetraphenylborate Salt of Atropine (R): Synthesis and X-ray Structure of Tetraphenyl-lambda(4)-borane, (1R,3r,5S,8s)-3-((3-Hydroxy-2-phenylpropanoyl)oxy)-8-methyl-8-azabicyclo[3.2.1]octan-8-ium Salt

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Tetraphenylborate Salt of Atropine (R): Synthesis and X-ray Structure of Tetraphenyl-lambda(4)-borane, (1R,3r,5S,8s)-3-((3-Hydroxy-2-phenylpropanoyl)oxy)-8-methyl-8-azabicyclo[3.2.1]octan-8-ium Salt

机译：无丙酮（R）的四苯硼酸盐：四苯基 - λ（4） - 硼（4） - 硼（1R，3R，5s，8s）-3 - （（3-羟基-2-苯基丙酰基）氧）的合成和X射线结构）-8 - 甲基-8-氮杂双环[3.2.1]辛烷-8-Ium盐

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The title compound, tetraphenylborate salt of atropine (RS)-(8-Methyl-8-azabicyclo[3.2.1]oct-3-yl) 3-hydroxy-2-phenylpropanoate tetraphenylborate salt, was prepared by the reaction of (RS)-(8-Methyl-8-azabicyclo[3.2.1]oct-3-yl) 3-hydroxy-2-phenylpropanoate sulfate (2:1) salt with sodium tetraphenylborate in deionized water at ambient temperature through anion exchange reaction. Colorless crystals of the title compound suitable for X-ray structural analysis were obtained by slow evaporation from acetonitrile. The title compound crystallizes in the triclinic sp. gr. P (1) over bar with a = 9.7989(5)angstrom , b = 9.8203(5)angstrom , c = 18.6099(9)angstrom , alpha = 81.356(2)degrees, beta = 80.616(2)degrees, gamma = 67.704(2)degrees, V = 1627.05(14)angstrom(3), Z = 2.

机译：通过（RS）的反应，通过（RS）的反应制备（RS）的三苯甲酸盐（RS） - （RS） - （8-甲基-8-氮杂双环[3.2.1]苯基丙二酸盐四苯基硼酸盐的标题化合物 - （8-甲基-8-氮杂双环[3.2.1] 10-3-烷基二乙酰丙二醇酸酯3-羟基-2-苯基丙酸盐（2：1）硫酸盐，通过阴离子交换反应在环境温度下去离子水中的硫酸钠。通过从乙腈缓慢蒸发获得适用于X射线结构分析的标题化合物的无色晶体。标题化合物在三级SP中结晶。 GR。 P（1）通过A = 9.7989（5）埃ang杆，B = 9.8203（5）埃，C = 18.6099（9）埃，α= 81.356（2）度，β= 80.616（2）度，伽马= 67.704 （2）度，v = 1627.05（14）埃（3），Z = 2。

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《Crystallography reports》 |2017年第7期|共6页
作者
Mostafa G. A. E.; Ghabbour H. A.; Abdel-Aziz H. A.;
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King Saud Univ Dept Pharmaceut Chem Coll Pharm POB 2457 Riyadh 11451 Saudi Arabia;

King Saud Univ Dept Pharmaceut Chem Coll Pharm POB 2457 Riyadh 11451 Saudi Arabia;

King Saud Univ Dept Pharmaceut Chem Coll Pharm POB 2457 Riyadh 11451 Saudi Arabia;

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1. Tetraphenylborate Salt of Atropine (R): Synthesis and X-ray Structure of Tetraphenyl-lambda(4)-borane, (1R,3r,5S,8s)-3-((3-Hydroxy-2-phenylpropanoyl)oxy)-8-methyl-8-azabicyclo[3.2.1]octan-8-ium Salt [J] . Mostafa G. A. E., Ghabbour H. A., Abdel-Aziz H. A. Crystallography reports . 2017,第7期

机译：无丙酮（R）的四苯硼酸盐：四苯基 - λ（4） - 硼（4） - 硼（1R，3R，5s，8s）-3 - （（3-羟基-2-苯基丙酰基）氧）的合成和X射线结构）-8 - 甲基-8-氮杂双环[3.2.1]辛烷-8-Ium盐
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Tetraphenylborate Salt of Atropine (R): Synthesis and X-ray Structure of Tetraphenyl-lambda(4)-borane, (1R,3r,5S,8s)-3-((3-Hydroxy-2-phenylpropanoyl)oxy)-8-methyl-8-azabicyclo[3.2.1]octan-8-ium Salt

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