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Associations between dual use of e-cigarettes and smoking cessation: A prospective study of smokers in England

机译：电子卷烟和吸烟的双重使用与吸烟的关联：英格兰吸烟者的前瞻性研究

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Background: It has been claimed that use of e-cigarettes in combination with cigarettes outside of a quit attempt ('dual use') reduces quitting among smokers. This study aimed to assess whether dual e-cigarette users have lower smoking cessation rates than (i) exclusive cigarette smokers or (ii) dual users of nicotine replacement therapy (NRT) and cigarettes. Methods: Prospective cohort study of 1,498 smokers in England. The independent variable was dual use of e-cigarettes (n = 292), dual use of NRT (n = 117), or exclusive smoking (n = 1089), assessed at baseline. Outcomes were overall quit rate, past-year quit attempts, and success of quit attempts at 12-month follow-up. Baseline sociodemographic and smoking-related covariates were included. Results: Overall quit rates were not lower in dual e-cigarette users than exclusive smokers (OR = 1.31, 0.90-1.89). Dual users of e-cigarettes were more likely than exclusive smokers to make a quit attempt, but this difference was not significant after adjustment for covariates (OR = 1.27, 95%CI 0.95-1.69). Among those attempting to quit, success rates did not differ significantly. Dual users of e-cigarettes were less likely to make a quit attempt than dual users of NRT (OR = 0.61, 95%CI 0.38-0.98) but the success rate of quit attempts and overall quit rates did not differ significantly. Conclusions: In England, dual use of e-cigarettes is not associated with reduced overall quit rates compared with exclusive smoking or dual use of NRT. However, dual use of e-cigarettes is associated with a slightly higher quit attempt rate than exclusive smoking but lower than dual use of NRT.
机译：背景：已声称，在退出尝试之外的卷烟组合使用电子烟（'双使用'）减少吸烟者中的戒烟。本研究旨在评估双电子卷烟用户是否具有比（i）独家香烟吸烟者或（ii）尼古丁替代疗法（NRT）和香烟的双重用户的吸烟率较低。方法：英格兰1,498名吸烟者的前瞻性队列研究。独立变量是双重使用电子香烟（n = 292），NRT（n = 117）的双重使用，或在基线评估的独家吸烟（n = 1089）。结果是整体戒烟率，过去的戒烟尝试，并在12个月的随访时戒烟尝试成功。包括基线社会阶层和与吸烟有关的协变量。结果：双电子卷烟用户的整体退出率不低于独家吸烟者（或= 1.31,0.90-1.89）。电子卷烟的双重用户比独家吸烟者更有可能进行戒烟，但在调整协变量（或= 1.27,95％CI 0.95-1.69）时，这种差异并不显着。在试图戒烟的人中，成功率没有显着差异。电子卷烟的双重用户不太可能比NRT的双用户（或= 0.61,95％CI 0.38-0.98）进行退出尝试，但退出尝试的成功率和总戒烟率没有显着差异。结论：在英格兰，与NRT的独家吸烟或双重使用相比，对E-rubettes的双重使用无关。然而，对电子烟的双重使用与略高的戒烟率而不是独家吸烟，但低于NRT的双重使用。

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