X?ray Structure Determination of Ion-Channel Crystalline Architectures Close to Bilayer Membrane-Confined Conditions

Mihail Barboiu; Dan Dumitrescu; Arie van der Lee

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X?ray Structure Determination of Ion-Channel Crystalline Architectures Close to Bilayer Membrane-Confined Conditions

机译：接近双层膜限制条件的离子通道晶体结构的X射线结构测定

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Experimental evidence presented in this paper shows that long-range crystalline order as observed in the macrocyclic heteroditopic receptors’ single-crystal structures is preserved when embedded in the bilayer membranes. Investigations presented here showed that MCM_41-type mesoporous hydrophobic hybrids can be used as biomimetic platforms for ion-channel biomimetic structure elucidation, while showing similar hydrophobic interactions with confined ligands/receptors as in bilayer membranes. This gives access to information concerning the structural pictures of the bilayer’s confined ion-channel structures, as well as of their relatives in the presence of ion effectors.

机译：本文提供的实验证据表明，当嵌入双层膜中时，在大环异双位受体的单晶结构中观察到的长程晶体顺序得以保留。此处进行的研究表明，MCM_41型介孔疏水杂种可以用作离子通道仿生结构阐明的仿生平台，同时显示出与局限性配体/受体相似的疏水性相互作用（如双层膜）。这样就可以访问有关双层受限离子通道结构以及在存在离子效应器的情况下其亲属的结构图的信息。

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《Crystal growth & design》 |2014年第6期|共7页
作者
Mihail Barboiu; Dan Dumitrescu; Arie van der Lee;
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正文语种 eng
中图分类晶体学;
关键词
mesoporous; elucidation; structures;

机译：介孔;阐明;结构;

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专利

1. X?ray Structure Determination of Ion-Channel Crystalline Architectures Close to Bilayer Membrane-Confined Conditions [J] . Mihail Barboiu, Dan Dumitrescu, Arie van der Lee Crystal growth & design . 2014,第6期

机译：接近双层膜限制条件的离子通道晶体结构的X射线结构测定
2. Determination of tungsten layer profiles in bilayer structures using X-ray reflectivity method [J] . Xu Y, Wang ZS, Wang B, Chinese physics letters . 2007,第2期

机译：使用X射线反射率法测定双层结构中的钨层轮廓
3. Determination of Tungsten Layer Profiles in Bilayer Structures Using X-Ray Refiectivity Method [J] . XU Yao, CHEN Ling-Yan, WANG Zhan-Shan, 中国物理快报：英文版 . 2007,第002期

机译：用X射线反射法测定双层结构中的钨层轮廓。
4. Analysis of Microscopic Strain and Crystalline Structure in Ge/Ge_(1-x)Sn_x Fine Structures by using Synchrotron X-ray Microdiffraction [C] . S. Ike, O. Nakatsuka, Y. Inuzuka, PRiME Joint International Meeting of the Electrochemical Society, the Electrochemical Society of Japan, and the Korean Electrochemical Society . 2016

机译：使用Synchrotron X射线微缩合通过GE / GE_（1-X）SN_X细结构中微观应变和晶体结构分析
5. X-RAY DIFFRACTION STUDIES ON LAMELLAR STRUCTURES OF LIPID BILAYERS AND OF LIPID-PROTEIN COMPLEXES [D] . 猪子, 洋二 -1

机译：脂质双分子层和脂质-蛋白质复合物的层状结构的X射线衍射研究
6. Fluid bilayer structure determination by the combined use of x-ray and neutron diffraction. I. Fluid bilayer models and the limits of resolution. [O] . M C Wiener, S H White 1991

机译：通过结合使用X射线和中子衍射来确定流体双层结构。一流体双层模型及其分辨率极限。
7. Fluid bilayer structure determination by the combined use of x-ray and neutron diffraction. I. Fluid bilayer models and the limits of resolution. [O] . Wiener, M C, White, S H 1991

机译：通过结合使用X射线和中子衍射来确定流体双层结构。一，流体双层模型及其分辨率极限。

X?ray Structure Determination of Ion-Channel Crystalline Architectures Close to Bilayer Membrane-Confined Conditions

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