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首页> 外文期刊>Aging, neuropsychology and cognition >Conceptual elaboration versus direct lexical access in WAIS-similarities: differential effects of white-matter lesions and gray matter volumes
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Conceptual elaboration versus direct lexical access in WAIS-similarities: differential effects of white-matter lesions and gray matter volumes

机译:WAIS-相似之处的概念阐述与直接词汇接入:白品病变和灰质体积的差异效果

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摘要

Wechsler Adult Intelligence Scale (WAIS) subscale Similarities have been classified as a test of either verbal comprehension or of inductive reasoning. The reason may be that items divide into two categories. We tested the hypothesis of heterogeneity of items in WAIS-Similarities. Consecutive patients at a memory clinic and healthy controls participated in the study. White-matter hyperintensities (WMHs) and normalized temporal lobe volumes were measured based on Magnetic resonance Imaging (MRI), and tests of verbal memory and attention were used in addition to WAIS-Similarities to collect behavioural data. Factor analysis supported the hypothesis that two factors are involved in the performance of WAIS-similarities: (1) semiautomatic lexical access and (2) conceptual elaboration. These factors were highly correlated but provided discriminative diagnostic information: In logistic regression analyses, scores of the lexical access factor and of the conceptual elaboration factor discriminated patients with mild cognitive impairment from Alzheimer's disease patients and from healthy controls, respectively. High scores of WMH, indicating periventricular white-matter lesions, predicted factor scores of direct lexical access but not those of conceptual elaboration, which were predicted only by medial and lateral temporal lobe volumes.
机译:韦斯勒成人智能量表(WAIS)分码相似度已被归类为对言语理解或归纳推理的测试。原因可能是物品分为两类。我们测试了WAIS-相似性项目的异质性的假设。在记忆诊所和健康控制的连续患者参加了该研究。基于磁共振成像(MRI)测量白料高度增长(WMHS)和归一化的时间叶片,除了GAIS-相似之处,使用口头记忆和注意力以收集行为数据。因子分析支持两个因素涉及WAIS-相似性的两个因素:(1)半自动词汇通行和(2)概念阐述。这些因素具有高度相关性,但提供了判别诊断信息:在逻辑回归分析中,词汇存取因子和概念阐述因子分别与阿尔茨海默病患者病患者和健康对照有轻度认知障碍患者的分数。 WMH的高分性,表明脑室白物病变,预测因子评分直接词汇进入,而不是概念性阐述,仅通过内侧和横向颞叶体积预测。

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