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Penile Rehabilitation Therapy with PDE-V Inhibitors Following Radical Prostatectomy: Proceed with Caution

机译:PDE-V抑制剂的阴茎康复治疗术后前列腺切除术:谨慎行事

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摘要

Penile rehabilitation therapy following radical prostatectomy is a much debated topic. Erectile dysfunction is still a significant contributor to postoperative morbidity following radical prostatectomy, despite meticulous nerve-sparing technique. Secondary smooth muscle changes in the penis have been identified as the underlying causes of penile atrophy, veno-occlusive dysfunction, and fibrosis. Initial observations that intracavernous injection therapies used on a regular basis postoperatively resulted in improvements in the return of spontaneous erectile function led to the development of penile rehabilitation protocols. Chronic dosing of PDE-V inhibitors is now commonly used by urologists after radical prostatectomy. Despite the current enthusiasm of penile rehabilitation therapy, current scientific evidence with clinical trials is still limited.
机译:在根治性前列腺切除术后的阴茎康复治疗是一个很多辩论的话题。 尽管细致的神经保留技术,勃起功能障碍仍然是术后前列腺切除术后的术后发病率的重要因素。 阴茎中的次级平滑肌变化已被确定为阴茎萎缩,静脉闭塞功能障碍和纤维化的潜在原因。 初步观察:在术后术后术后使用的内部注射疗法导致自发勃起函数返回的改善导致了阴茎康复方案的发展。 在自由基前列腺切除术后,现在通常使用PDE-V抑制剂的慢性剂量。 尽管目前对阴茎康复治疗的热情,但目前具有临床试验的科学证据仍然有限。

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