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首页> 外文期刊>AIDS care. >Substance use and HIV-risk behaviors among HIV-positive men who have sex with men in China: repeated measures in a cohort study design
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Substance use and HIV-risk behaviors among HIV-positive men who have sex with men in China: repeated measures in a cohort study design

机译：与中国男子发生性关系的艾滋病毒阳性男性的物质使用和艾滋病毒风险行为：在队列研究设计中反复措施

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摘要

Global literature revealed that seropositive men who have sex with men (MSM) posed an even higher risk compared to their seronegative counterparts. Identifying risk factors that contribute to HIV-risk behaviors will help to curb the rapid HIV transmission among this group. Our hypothesis was that MSM with substance use were more likely to conduct HIV-risk behaviors, even after accounting for repeated measures. In the current study, we employed a cohort study design by following a group of 367 HIV-positive MSM up to four visits for one year to collect information regarding their sexual behaviors and history of substance use in the past three months. We used Generalized Estimating Equations (GEE) models to account both within-and between-subject variation when assessing associations between substance use and HIV-risk behaviors. A total of 367 MSM were included at the baseline with a mean age of 29.6 years. After accounting for potential confounders and time-varying effects, our models indicated that drug and alcohol use increase HIV risks at the population level by increasing risks of drinking alcohol before sex, having unprotected sex with men and seropositive partners, having more lifetime female sex partners and having a higher number of male sexual partners in the past three months. The current study is one of the first studies with repeated measures to evaluate the association between substance use and sexual risk behaviors among MSM in China. Findings in the current study have several implications for future research. We call for more rigorous study design for future research to better capture changes of risky behaviors among this at-risk population.
机译：全球文献透露，与男人（MSM）发生性关系的血清阳性男性与其血型对应物相比造成了更高的风险。识别有助于艾滋病毒风险行为的危险因素将有助于抑制该组中的快速艾滋病病毒疫情。我们的假设是，即使在考虑反复措施后，我们的假设也更有可能进行艾滋病毒风险行为。在目前的研究中，我们通过遵循一组367名艾滋病毒阳性MSM雇用队列研究设计一年，以收集过去三个月内有关其性行为和物质历史的信息。我们使用广义估计方程（GEE）模型在评估物质使用和艾滋病毒风险行为之间的关联时审查对象变异。基线共有367名MSM，平均年龄为29.6岁。在考虑潜在的混乱和时变效应后，我们的模型表明，通过增加性别前饮酒的风险，药物和酒精使用药物和酒精在人口水平上增加了艾滋病病毒风险，并具有与男性和血清阳性伙伴的无保护性，具有更多终身女性性伙伴在过去的三个月里，在过去的三个月里有更多的男性性伴侣。目前的研究是重复措施的第一项研究之一，以评估中国MSM中的物质使用和性风险行为之间的关联。目前研究中的调查结果对未来的研究有几种影响。我们呼吁更严格的研究设计，以便将来的研究，以更好地捕捉到风险群体中的风险行为的变化。

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  • 来源
    《AIDS care.》 |2017年第6期|共10页
  • 作者

    Zhang Chen; Liu Yu; Sun Xiaoyun; Wang Juan; Lu Hong-Yan; He Xiong; Zhang Heng; Ruan Yu-Hua; Shao Yiming; Vermund Sten H.; Qian Han-Zhu;

  • 作者单位

    Vanderbilt Univ Vanderbilt Inst Global Hlth 2525 West End Ave Suite 750 Atlanta GA 30322 USA;

    Vanderbilt Univ Vanderbilt Inst Global Hlth 2525 West End Ave Suite 750 Atlanta GA 30322 USA;

    Xicheng Ctr Dis Control &

    Prevent Beijing Peoples R China;

    Chaoyang Ctr Dis Control &

    Prevent Beijing Peoples R China;

    Beijing Ctr Dis Control &

    Prevent Beijing Peoples R China;

    Beijing Ctr Dis Control &

    Prevent Beijing Peoples R China;

    Collaborat Innovat Ctr Diag &

    Treatment Infect Di State Key Lab Infect Dis Prevent &

    Control SKLID;

    Natl Ctr AIDS STD Control &

    Prevent NCAIDS Chinese Ctr Dis Control &

    Prevent China CDC Beijing;

    Chinese Ctr Dis Control &

    Prevent China CDC Beijing Peoples R China;

    Vanderbilt Univ Vanderbilt Inst Global Hlth 2525 West End Ave Suite 750 Atlanta GA 30322 USA;

    Ctr Dis Control &

    Prevent Atlanta GA USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 传染病;
  • 关键词

    Substance use; HIV risk; men who have sex with men; China; repeated measures;

    机译：物质使用;艾滋病毒风险;与男人发生性关系的男性;中国;重复措施;

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