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Changes in risk behaviors among Thai men who have sex with men and transgender women enrolled in the test and treat cohort

机译：与男性和转型妇女发生性关系的泰国男性风险行为的变化，注册了测试和治疗队列

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摘要

The test-and-treat approach has the potential to reduce high-risk sexual behaviors by linking high-risk individuals to health education, although this has not been proven yet. We used longitudinal data from the Test and Treat Demonstration Project among Thai men who have sex with men (MSM) and transgender women (TGW) who were not known to be HIV-positive to analyze changes in risk behaviors during the 24-month study period categorized by three groups: HIV-negative without seroconversion, seroconverters, and HIV-positive at enrollment. Five binary risk behavior outcomes - laboratory-diagnosed sexually transmitted infections (STIs); multiple sexual partners, unprotected anal intercourse, self-perceived HIV risk, and amphetamine-type stimulants use in the past month - were assessed. Among 689 participants, with a mean (SD) age of 23.1 (6.2) years, 165 participants were diagnosed with HIV: 115 at enrollment and 50 with seroconversions. HIV-positive participants at enrollment showed significant reductions in all five behavioral risk outcomes. Seroconverters demonstrated higher risks at enrollment than HIV-negative participants, and continued to practice high-risk behaviors even after seroconversion despite a significant reduction in self-perceived moderate-to-high HIV risk. Continuation of risk behaviors among seroconverters could negatively affect the ending AIDS goal, thus the integration of other effective preventive measures into HIV/STIs management programs are needed.
机译：测试和治疗方法通过将高危人员与健康教育联系起来，有可能降低高风险性行为，尽管这尚未证明。我们使用了与男性（MSM）和转型女性（TGW）发生性关系的泰国男性的测试和治疗示范项目，他未知为HIV阳性，以分析24个月的研究期间风险行为的变化分类为三组：HIV阴性没有血清转换，血管转换器和艾滋病毒阳性的注册。五个二元风险行为结果 - 实验室诊断为性传播感染（STI）;评估了多种性伴侣，未受保护的肛交，自我感知的艾滋病毒风险，以及过去一个月的Amphetamine型兴奋剂使用。在689名参与者中，平均（SD）年龄为23.1（6.2）岁，165名参与者被诊断为艾滋病毒：115次注册，50名与血清贷款。艾滋病毒阳性参与者在入学期间表现出所有五种行为风险结果的显着减少。 Seroconverters在注册时比HIV阴性参与者展现出更高的风险，并且仍然在血清转换之后继续练习高风险的行为，尽管自我感知的中度至高的艾滋病毒风险显着降低。血管转换器中的风险行为延续可能会对结束助剂的目标产生负面影响，因此需要将其他有效预防措施的整合到HIV / STIS管理方案中。

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