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Psychosocial factors and treatment adherence in paediatric HIV/AIDS.

机译:儿科艾滋病毒/艾滋病的心理社会因素和治疗依从性。

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摘要

A social ecological model provides a promising framework for understanding the individual, family, and societal factors contributing to non-adherence to treatment of paediatric HIV. This study explored which factors relevant to this model are associated with caregivers' adherence and child health outcomes. A cross-sectional design was utilized to assess relationships among current individual, familial, extra-familial factors, caregiver adherence, and viral load. Data were collected from 43 caregivers, and viral load data were obtained from the medical records of their HIV+ children. Caregiver drug and alcohol use and HIV+ status were associated with non-adherence and elevated viral load. Negative outcome expectancy was associated with lower adherence but was not significant in the multivariate analyses. Family factors were not significant, but these measures had low reliability in this sample. Extra-familial factors such as dissatisfaction with medical specialty care and more stressful life events werenot directly associated with adherence but were related to increased caregiver substance use. Results of this first study to explore multiple predictors of adherence and health outcomes in paediatric HIV require replication with larger samples, but findings suggest caregiver characteristics that place children at risk for disease progression due to poor adherence to treatment.
机译:社会生态模型为理解有助于不遵守儿科艾滋病毒治疗的个人,家庭和社会因素提供了一个有前途的框架。本研究探讨了与该模型相关的因素与护理人员的依从性和儿童健康结果相关。利用横截面设计来评估当前个体,家族性,家族性因素,护理人员依赖和病毒载量之间的关系。数据从43名护理人员收集,并且从艾滋病毒+儿童的病历中获得病毒载荷数据。护理人员药物和酒精使用和HIV +状态与非粘附性和病毒载荷升高有关。负面结果预期率与较低的粘附相关,但在多变量分析中并不重要。家庭因素并不重要,但这些措施在该样品中具有很低的可靠性。额外的家庭因素,如医学专业护理的不满和更加紧张的生活事件,与依从性直接相关但与摄取者物质的使用增加有关。第一次研究探索儿科艾滋病毒的多重预测因子的第一次研究需要用较大的样品复制,但调查结果表明护理人员特征,使儿童因依赖于治疗而导致疾病进展的风险。

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