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首页> 外文期刊>AIDS care. >Reducing medication errors involving antiretroviral therapy with targeted electronic medical record modifications
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Reducing medication errors involving antiretroviral therapy with targeted electronic medical record modifications

机译：减少涉及抗逆转录病毒治疗的药物误差，具有目标电子医疗记录修改

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Medication errors are common among HIV-infected patients on anti-retroviral therapy (ART), especially when transitioning to the inpatient setting. In previous studies, medication error rates among hospitalized patients on ART have been reported to exceed 50%. When patients receiving ART are admitted to the hospital, medication errors can be prevented through optimization of administration instructions and dosing defaults in order-entry screens in the electronic medical record (EMR). We sought to evaluate the impact of EMR modifications (defaulted doses, frequencies, and administration instructions) implemented to improve the order-entry process and reduce errors. All adult patients admitted between 10/1/2010-3/31/2012 (pre-EMR modification) and 10/1/2013-3/31/2014 (post-EMR modification) that continued on ART upon admission were included. The primary outcome was the overall rate of medication errors identified through review by the antimicrobial stewardship program (ASP). We also characterized the types of medication errors identified during the two time periods. Following EMR modifications, the medication error rate identified through ASP review was reduced from 50.2% to 28.2% (P < 0.01). The number of medication related errors relating to dosage (regimens requiring dose optimization, renal dose adjustment, and dose timing) were reduced by 22% (P < 0.01). Modifications at the anti-retroviral medication order-entry screens in the EMR significantly reduced medication errors, particularly with respect to dosing and dose timing.
机译：在抗逆转录病毒治疗（ART）上的艾滋病毒感染患者中常见的药物误差是常见的，特别是在过渡到住院环境时。在先前的研究中，据报道，艺术患者的药物错误率超过50％。当接受艺术的患者进入医院时，可以通过在电子医疗记录（EMR）中的秩序入口屏幕中优化给药说明和给药违约来防止药物错误。我们试图评估实施EMR修改的影响（默认剂量，频率和管理说明），以改善秩序进入过程并减少错误。所有成年患者均在入院时持续的10/1 / 2010-3 / 31/31 / 2012年（EMR修改前）和2014年第10/1 / 2013-3/31/31/31/31/13/13/124（EMR修改后）。主要结果是通过抗微生物管理计划（ASP）通过审查确定的药物误差的总体速率。我们还表征了在两次期间识别的药物误差类型。在EMR修饰之后，通过ASP评论确定的药物错误率从50.2％降至28.2％（P <0.01）。与剂量相关的药物相关误差（需要剂量优化的方案，肾剂量调节和剂量时序）减少22％（P <0.01）。 EMR中抗逆转录病毒用药秩序筛网的修饰显着降低了药物误差，特别是对剂量和剂量定时。

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