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The impact of HIV diagnosis on length of hospital stay in NewYork City, NY, USA

机译:HIV诊断对美国纽约纽约市住院时间长度的影响

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While hospitalizations among people living with human immunodeficiency virus (PLWH) have been elevated in the past compared to their uninfected counterparts, the introduction of antiretroviral therapy (ART) has resulted in great strides in controlling symptomatic infection. However, research largely overlooks important differences among HIV-infected individuals, primarily PLWH who are symptomatic versus those who are asymptomatic. We conducted a retrospective study assessing the length of hospital stay among 717,237 admissions from three hospitals in the NewYork City area. Using zero-truncated negative binomial regression we documented trends in length of hospital stay among individuals who are HIV positive (with symptoms versus those without symptoms) compared to HIV-negative patients over nine consecutive years, from 2006 to 2014. Approximately 0.85% of the admissions were infected with asymptomatic HIV (n=6,131), while 1.43% of admissions were infected with symptomatic HIV (n=10,271). The length of stay (LOS) among symptomatic HIV-infected admissions was 32.0% (95% CI: 29.7%-34.2%) longer than LOS in the general admissions. The mean LOS dropped about 1.5% (95% CI: 1.5%-1.6%) per year in the study sample. The LOS in inpatients with asymptomatic HIV had the same LOS as the general inpatient population. Our findings highlight the need for comprehensive strategies to reduce length of hospitalization among HIV-infected individuals.
机译:虽然与人类免疫缺陷病毒(PLWH)的住院期间与过去感染的对应物相比,在过去升高的情况下,但引入抗逆转录病毒治疗(ART)在控制症状感染方面导致了巨大进展。然而,研究在很大程度上忽略了艾滋病毒感染的个体的重要差异,主要是PLWH谁是症状与无症状的人。我们进行了一项回顾性研究,评估了纽约市区三家医院的717,237名入院中的住院时间。使用零截断的负二项式回归,我们记录了与艾滋病毒阳性的患者(症状与症状的症状)的患者的趋势记录在2006年至2014年的患者中,从2006年到2014年。约0.85%入院患有无症状艾滋病毒(n = 6,131),而1.43%的入院感染有症状HIV(n = 10,271)。比洛杉矶的症状艾滋病毒感染入院中的住宿时间(LOS)为32.0%(95%CI:29.7%-34.2%)。在研究样品中,平均洛杉矶的平均值下降约1.5%(95%:1.5%-1.6%)。具有无症状艾滋病毒的住院患者的LOS具有与一般住院人口相同的洛杉矶。我们的研究结果强调了需要综合策略,以减少艾滋病毒感染的个体的住院时间。

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