Adherence to antiretroviral therapy, stigma and behavioral risk factors in HIV-infected adolescents in Asia

Prasitsuebsai Wasana; Sethaputra Chuenkamol; Lumbiganon Pagakrong; Hansudewechakul Rawiwan; Chokephaibulkit Kulkanya; Khanh Huu Truong; Lam Van Nguyen; Razali Kamarul Azahar Mohd; Yusoff Nik Khairulddin Nik; Fong Moy Siew; Teeraananchai Sirinya; Ananworanich Jintanat; Durier Nicolas

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Adherence to antiretroviral therapy, stigma and behavioral risk factors in HIV-infected adolescents in Asia

机译：亚洲艾滋病毒感染青少年抗逆转录病毒治疗，耻辱和行为危险因素的粘附性

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We studied behavioral risks among HIV-infected and uninfected adolescents using an audio computer-assisted self-interview. A prospective cohort study was initiated between 2013 and 2014 in Malaysia, Thailand, and Vietnam. HIV-infected adolescents were matched to uninfected adolescents (4:1) by sex and age group (12-14 and 15-18 years). We enrolled 250 HIV-infected (48% male; median age 14.5 years; 93% perinatally infected) and 59 uninfected (51% male; median age 14.1 years) adolescents. At enrollment, HIV-infected adolescents were on antiretroviral therapy (ART) for a median (IQR) of 7.5 (4.7-10.2) years, and 14% had HIV-RNA 1000copies/mL; 19% reported adherence 80%. Eighty-four (34%) HIV-infected and 26 (44%) uninfected adolescents reported having ever smoked cigarettes or drunk alcohol (p=0.13); 10% of HIV-infected and 17% of uninfected adolescents reported having initiated sexual activity; 6 of the HIV-infected adolescents had HIV-RNA 1000copies/mL. Risk behaviors were common among adolescents, with few differences between those with and without HIV.

机译：我们使用音频计算机辅助自拍研究了艾滋病毒感染和未感染的青少年之间的行为风险。在2013年和2014年在马来西亚，泰国和越南之间启动了一个未来的队列研究。艾滋病毒感染的青少年与性别和年龄组（12-14和15-18岁）与未感染的青少年（4：1）匹配。我们注册了250名艾滋病毒感染（48％的男性;中位年龄14.5岁;占产病93％）和59个未感染的（51％的男性;中位年龄14.1岁）青少年。在注册时，艾滋病毒感染的青少年是抗逆转录病毒治疗（ART），中位数（IQR）为7.5（4.7-10.2）岁，14％患有HIV-RNA＆GT; 1000倍/ mL; 19％报告申请申请效果。八十四（34％）艾滋病毒感染和26名（44％）未感染的青少年报告曾经吸烟或醉酒饮酒（P = 0.13）; 10％的艾滋病毒感染和17％的未感染的青少年报告已发起性活动;艾滋病毒感染的青少年中有6例HIV-RNA＆ 1000厘米/ ml。危险行为在青少年中很常见，在没有艾滋病毒的人之间存在很少的差异。

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来源
《AIDS care.》 |2018年第6期|共7页
作者
Prasitsuebsai Wasana; Sethaputra Chuenkamol; Lumbiganon Pagakrong; Hansudewechakul Rawiwan; Chokephaibulkit Kulkanya; Khanh Huu Truong; Lam Van Nguyen; Razali Kamarul Azahar Mohd; Yusoff Nik Khairulddin Nik; Fong Moy Siew; Teeraananchai Sirinya; Ananworanich Jintanat; Durier Nicolas;
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作者单位

Thai Red Cross AIDS Res Ctr HIV Netherlands Australia Thailand Res Collaborat Bangkok Thailand;

TREAT Asia AmfAR 388 Sukhumvit Rd Suite 2104 Bangkok 10110 Klongtoey Thailand;

Khon Kaen Univ Srinagarind Hosp Fac Med Khon Kaen Thailand;

Chiangrai Prachanukroh Hosp Chiang Rai Thailand;

Mahidol Univ Fac Med Siriraj Hosp Bangkok Thailand;

Childrens Hosp 1 Ho Chi Minh City Vietnam;

Natl Hosp Pediat Hanoi Vietnam;

Hosp Kuala Lumpur Inst Pediat Kuala Lumpur Malaysia;

Hosp Raja Perempuan Zainab II Kelantan Malaysia;

Hosp Likas Kota Kinabalu Malaysia;

Thai Red Cross AIDS Res Ctr HIV Netherlands Australia Thailand Res Collaborat Bangkok Thailand;

Walter Reed Army Inst Res US Mil HIV Res Program Silver Spring MD USA;

TREAT Asia AmfAR 388 Sukhumvit Rd Suite 2104 Bangkok 10110 Klongtoey Thailand;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
HIV; adolescents; Asia; adherence; stigma;

机译：艾滋病毒;青少年;亚洲;坚持;耻辱;

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专利

1. Adherence to antiretroviral therapy, stigma and behavioral risk factors in HIV-infected adolescents in Asia [J] . Prasitsuebsai Wasana, Sethaputra Chuenkamol, Lumbiganon Pagakrong, AIDS care. . 2018,第6期

机译：亚洲艾滋病毒感染青少年抗逆转录病毒治疗，耻辱和行为危险因素的粘附性
2. Factors associated with non-adherence to antiretroviral therapy among HIV-infected adolescents aged 15-19 years: a snapshot from the Mother and Child Center in Yaounde, Cameroon [J] . Martial Wandji Lantche, Joseph Fokam, Anne-Jocelyne Nguemedyam Cheudjui, Pan African Medical Journal . 2021,第a期

机译：与15-19岁的艾滋病毒感染青少年抗逆转录病毒治疗相关的因素：喀麦隆雅温得母和儿童中心的快照
3. The role of family factors in antiretroviral therapy (ART) adherence self-efficacy among HIV-infected adolescents in southern Uganda [J] . Proscovia Nabunya, Ozge Sensoy Bahar, Bin Chen, BMC Public Health . 2020,第1期

机译：家庭因素在乌干达南部艾滋病毒感染青少年中抗逆转录病毒治疗（艺术）依从性自我疗效的作用
4. Effect of highly active antiretroviral therapy (HAART) on lipid abnormalities in HIV-infected patients [C] . Estari Mamidala 2011 international conference on medical information and bioengineering. . 2011

机译：高效抗逆转录病毒疗法（HAART）对HIV感染患者血脂异常的影响
5. Antiretroviral Therapy Adherence in Youth Living with HIV: Exploring the Role of Risk Behaviors, Health Promotion Behaviors and Depressive Symptoms [D] . Loew, Megan Marie. 2018

机译：艾滋病毒青年患者的抗逆转录病毒疗法依从性：探讨风险行为，健康促进行为和抑郁症状的作用
6. Adherence to antiretroviral therapy stigma and behavioral risk factors in HIV-infected adolescents in Asia [O] . Wasana Prasitsuebsai, Chuenkamol Sethaputra, Pagakrong Lumbiganon, -1

机译：坚持接受亚洲艾滋病毒感染青少年的抗逆转录病毒疗法污名和行为危险因素
7. Risk Factors for Suboptimal Antiretroviral Therapy Adherence in HIV-Infected Adolescents in Gaborone, Botswana: A Pilot Cross-Sectional Study [O] . Ndiaye, Maimouna, Nyasulu, Peter, Nguyen, Hoang, 2013

机译：在博茨瓦纳哈博罗内艾滋病毒感染的青少年中抗逆转录病毒疗法依从性欠佳的危险因素：一项横断面研究

Adherence to antiretroviral therapy, stigma and behavioral risk factors in HIV-infected adolescents in Asia

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