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首页> 外文期刊>AIDS care. >Sexual risk behaviors following circumcision among HIV-positive men in Rakai, Uganda
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Sexual risk behaviors following circumcision among HIV-positive men in Rakai, Uganda

机译：乌干达哈凯艾滋病毒阳性男子割礼后的性风险行为

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Objective: To determine whether circumcision of HIV-positive men is associated with increased subsequent sexual risk behaviors which may place their female partners at risk.Methods: Newly circumcised and uncircumcised HIV-positive men in the Rakai Community Cohort Study were followed from baseline (July 2013-January 2015) to determine trend in sexual risk behaviors and association of circumcision with subsequent sexual risk behaviors at follow up (February 2015-September 2016). Risk behaviors included sexual activity, alcohol before sex, transactional sex, multiple sex partners, casual sex partners, and inconsistent condom use with casual partners. The association was evaluated using modified Poisson regression, and sensitivity analyses were performed after multiple imputation with chained equations for missing data.Results: We identified 538 eligible men, of whom 113(21.0%) were circumcised at baseline and 425(79.0%) were uncircumcised. Men in fishing communities were more likely to be circumcised (p=0.032) as well as those exposed to targeted HIV messaging (p0.001). Overall, 188(34.9%) men were lost to follow up and most were uncircumcised (p=0.020). Among those followed up, behaviors remained largely unchanged with no differences by circumcision status. Transactional sex appeared to be associated with circumcision in unadjusted analyses (PR=1.58, 95%CI=1.01,2.48; p=0.045, p=0.05) and adjusted analyses (adj.PR=1.54, 95%CI=1.06,2.23; p=0.022). However, the association was no longer significant in sensitivity analyses after accounting for loss to follow up (adj.PR=1.43, 95%CI=0.98,2.08; p=0.066). No association with circumcision was observed for other sexual risk behaviors.Conclusion: We found no association between circumcision of HIV-positive men and subsequent sexual risk behavior.
机译：目的：确定艾滋病毒阳性男性的割礼是否与随后的性风险行为增加，这可能将女性合作伙伴置于风险。中间：Rakai社区队列研究中的新割礼和未经化的艾滋病毒阳性男性被遵循基线（7月2013年1月2015年1月）确定随后的性风险行为（2015年2月）的后续性风险行为与后续性风险行为的性风险行为与联系协会。风险行为包括性活动，性行为前的酒精，交易性行为，多重性伙伴，休闲性伴侣和休闲合作伙伴的避孕套使用不一致。使用改进的泊松回归评估该关联，并且在多个归因于缺失数据的链接方程之后进行敏感性分析。结果：我们确定了538名符合条件的男性，其中113（21.0％）在基线下割礼，425（79.0％）未化的。捕鱼社区的男性更有可能被割礼（p = 0.032）以及暴露于靶向HIV消息传递的人（P <0.001）。总体而言，188名（34.9％）人失去了跟进，大多数是未经化的（P = 0.020）。在那些后续的人中，行为在很大程度上不变，没有差异的情况下没有差异。交易性性别似乎与未经调整的分析中的割礼相关（pr = 1.58,95％ci = 1.01,2.48; p = 0.045，p = 0.05）和调整后的分析（adj.pr = 1.54,95％ci = 1.06,2.23; p = 0.022）。然而，在核算后的敏感性分析中，关联在呼吸后不再重要（adj.pr = 1.43,95％ci = 0.98,2.08; p = 0.066）。对于其他性风险行为没有观察到与割礼联接相关联。结论：我们发现艾滋病毒阳性男性的割礼和随后的性风险行为之间没有关联。

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