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Exploring the dynamics of ART adherence in the context of a mindfulness instruction intervention among youth living with HIV in Baltimore, Maryland

机译:马里兰州巴尔的摩艾滋病毒艾滋病病毒症患者中青年教学干预的背景下探索艺术遵守动态

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Youth living with HIV have sub-optimal rates of adherence to antiretroviral therapy (ART). Mindfulness instruction interventions have shown promise for improving medication adherence, but the effects and mechanisms of these interventions are still being explored among people living with HIV, including youth. In the context of a randomized controlled trial of the efficacy of a Mindfulness-Based Stress Reduction (MBSR) program on ART adherence and viral suppression among youth living with HIV, we conducted 44 iterative, semi-structured, in-depth interviews with 20 study participants (13-24 years) recruited from clinics at two academic centers in Baltimore, Maryland. Interviews explored the social context and psychosocial dynamics of ART adherence in the context of the MBSR intervention, compared with those in a control arm. We employed thematic content analysis to systematically code and synthesize textual interview data. Participants' challenges with ART adherence were often situated within an ongoing process of working to manage HIV as a stigmatized, chronic condition in addition to other intersecting social stigmas, inequalities, and stressors. Participation in the MBSR program and related group support allowed participants to non-judgmentally observe and accept difficult thoughts, feelings, and experiences associated with living with HIV and taking ART, which facilitated greater reported adherence. Mindfulness training may stimulate new perspectives and understanding, including greater self- and illness-acceptance among youth living with HIV, leading to improved HIV outcomes.
机译:艾滋病毒的青年具有抗逆转录病毒治疗(艺术)的副最优依赖性谨慎的指导干预措施表明了提高药物遵守的希望,但这些干预措施的影响和机制仍在居住在艾滋病毒(包括青年)的人们中探讨。在随机对照试验中,基于艾滋病病毒症的艺术依恋(MBSR)的艺术依从性和病毒镇压的疗效的疗效,我们进行了44次迭代,半结构化,深入访谈,与20项研究进行了44次迭代,半结构化参与者(13-24岁)在马里兰州巴尔的摩的两个学术中心招募诊所。与控制手臂中的人相比,采访探索了在MBSR干预的背景下的艺术遵守的社会背景和心理社会动态。我们使用主题内容分析来系统地编码和综合文本面试数据。与艺术遵守的挑战往往位于持续的工作过程中,以便在其他交叉社会柱头,不平等和压力源外,在持续的努力管理艾滋病病毒病毒症作为耻辱状况。参与MBSR计划和相关组支持允许参与者非评价遵守和接受与艾滋病毒和艺术相关的困难思想,感受和经验,这促进了更大的报告依从性。 Mindfulness培训可能会刺激新的观点和理解,包括与艾滋病毒的青年中的更大的自我和疾病,导致艾滋病毒结果改善。

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