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Psychological and behavioral barriers to ART adherence among PLWH in China: role of self-efficacy

机译：中国PLWH艺术遵守的心理和行为障碍：自我效能的作用

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摘要

Globally, optimal adherence to antiretroviral therapy (ART) is insufficient despite it is critical for maximum clinical benefits and treatment success among people living with HIV (PLWH). Many factors have been evidenced to influence medication adherence, including perceived barriers and self-efficacy. However, limited data are available regarding to psychological and behavioral barriers to ART adherence in China. Moreover, few studies have examined the mechanism of these two factors underlying HIV medication adherence. The aim of the current study is to examine the mediating role of adherence self-efficacy between perceived barriers and ART adherence among PLWH. Cross-sectional data were obtained from 2095 PLWH in Guangxi China who provided data on ART adherence. Participants reported their medication adherence, self-efficacy, barriers to ART adherence, as well as background characteristics. Results indicated a significant indirect effect from perceived barriers to medication adherence through adherence self-efficacy. Higher perceived psychological and behavioral barriers to ART adherence were related to lower adherence self-efficacy, which in turn was related to lower ART adherence. Self-efficacy could buffer the negative effects of perceived barriers on ART adherence. Future interventions to promote HIV medication adherence are recommended to focus on eliminating psychological and behavioral barriers, as well as increasing adherence self-efficacy.
机译：在全球范围内，尽管患有艾滋病毒（PLWH）的人们最大的临床益处和治疗成功至关重要，但对抗逆转录病毒治疗（ART）的最佳粘附性不足。许多因素已经证明了影响药物遵守，包括感知障碍和自我效能。但是，有关中国艺术遵守的心理和行为障碍有限的数据可以提供有限的数据。此外，很少有研究检测过艾滋病毒药物遵守的这两个因素的机制。目前的研究的目的是检查PLWH之间的障碍和艺术粘附之间的粘附自我效力的中介作用。广西中国的横断面数据从广西中国提供了艺术遵守数据。参与者报告了他们的药物依从性，自我效能，艺术遵守障碍，以及背景特征。结果表明，通过粘附自效从粘附依赖于药物依从性的显着间接效应。更高的感知心理和行为障碍与艺术粘附性较低的依从性自我效能相关，这反过来与较低的艺术粘附有关。自我效能可以缓冲艺术遵守的感知障碍的负面影响。建议将来促进艾滋病毒药物药物遵守的干预措施，专注于消除心理和行为障碍，以及增加遵守自我效能。

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